Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN1500 | Jatrophane 4 |
| 1. (2R*,3R*,4S*,5R*,7S*,8S*,9S*,l3S*,14S*,15R*)-2,5,9,14-Tetraacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxyjatropha-6(17),11E-diene(Jatrophane 4 ) and (2R*,3R*, 4S*,5R*,7S*,8S*,9S*,l3S*,14S*,15R*)-2,5,14-triacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxy-9-nicotinoyloxyjatropha-6(17),11E-diene(Jatrophane 3) exhibit significant antifeedant activity against a generalist plant-feeding insect, the cotton bollworm (Helicoverpa armigera), with EC50 values of 0.36 and 0.43 ug/cm2, respectively. | |
| BCN1499 | Jatrophane 5 |
| 1. Jatrophane 5 demonstrates the most powerful inhibition of P-gp, higher than R(+)-verapamil and tariquidar in colorectal multi-drug resistant (MDR) cells (DLD1-TxR). | |
| BCN4914 | Cinnamyl acetate |
| 1. Cinnamyl acetate is used as flavor and fragrance ingredient in food and cosmetic industries. | |
| BCN4915 | Spiradine F |
| 1. Spiradine F can significantly inhibit platelet-activating factor(PAF)-induced platelet aggregation in a concentration-dependent manner. | |
| BCN4916 | Sakakin |
| Orcinol glucoside(Sakakin) shows potent antioxidative and anxiolytic activities without sedative effects, it can improve depressive behaviour in chronic unpredictable mild stress (CUMS) rats by downregulating HPA axis hyperactivity and increasing BDNF expression and ERK1/2 phosphorylation in the hippocampus. | |
| BCN1497 | 9,17-Octadecadiene-12,14-diyne-1,11,16-triol |
| 1. (+)-9(Z),17-Octadecadiene-12,14-diyne-1,11,16-triol shows antibacterial activity against Bacillus subtilis and Pseudomonas fluorescens, antifungal activity against Cladosporium cucumerinum, moiluscicidal activity against Biomphalaria glabrata at low concentrations, and in addition it possesses haemolytic activity. | |
| BCN4918 | Ceanothic acid |
| 1. Ceanothic acid derivatives show cytotoxic effect against OVCAR-3 and HeLa cancer cell lines. | |
| BCN1494 | 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one |
| 1. 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one shows moderate cytotoxicity against a human lung carcinoma cell line. | |
