Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 3057 - 3064 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7625 | 2-ThioUTP tetrasodium salt |
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Potent and selective P2Y<sub>2</sub> agonist (EC<sub>50</sub> values are 0.035, 0.35 and 1.5 <span class='symbol'>μ</span>M for hP2Y<sub>2</sub>, hP2Y<sub>4</sub> and hP2Y<sub>6</sub> receptors respectively).
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| BCC7626 | Canrenone |
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Mineralocorticoid receptor antagonist. Active metabolite of spironolactone.
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| BCC7627 | LY 487379 hydrochloride |
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Positive allosteric modulator selective for mGlu<sub>2</sub> receptors. Potentiates glutamate-stimulated [<sup>35</sup>S]GTP<span class='symbol'>γ</span>S binding (EC<sub>50</sub> values are 1.7 and > 10 <span class='symbol'>μ</span>M for mGlu<sub>2</sub> and mGlu<sub>3</sub> receptors respectively). Devoid of any activity at mGlu<sub>5</sub> and mGlu<sub>7</sub> receptors. Promotes cognitive flexibility in a rat model.
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| BCC7628 | Rec 15/2615 dihydrochloride |
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Selective <span class='symbol'>α</span><sub>1B</sub>-adrenoceptor antagonist (K<sub>i</sub> values are 0.3, 1.9 and 2.6 nM at human <span class='symbol'>α</span><sub>1B</sub>, <span class='symbol'>α</span><sub>1A</sub> and <span class='symbol'>α</span><sub>1D</sub> receptors respectively).
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| BCC7629 | NPS ALX Compound 4a dihydrochloride |
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Potent and competitive 5-HT<sub>6</sub> antagonist (IC<sub>50</sub> = 7.2 nM, K<sub>i</sub> = 0.2 nM) that displays selectivity over other 5-HT and D<sub>2</sub> receptors.
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| BCC7630 | Oxprenolol hydrochloride |
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Non-selective β-adrenergic antagonist.
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| BCC7631 | PF 915275 |
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Potent and selective 11<span class='symbol'>β</span>-hydroxysteroid dehydrogenase type 1 (11<span class='symbol'>β</span>HSD1) inhibitor (K<sub>i</sub> = 2.3 nM) that displays little activity at 11<span class='symbol'>β</span>HSD2 (1.5% inhibition at 10 <span class='symbol'>μ</span>M). Inhibits the conversion of prednisone to prednisolone in human hepatocytes <em>in vitro</em> (EC<sub>50</sub> = 15 nM) and has antidiabetic activity <em>in vivo</em>. Orally active.
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| BCC7632 | Metyrapone |
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Cytochrome P450 inhibitor. Blocks glucocorticoid synthesis via inhibition of steroid 11-<span class='symbol'>β</span> hydroxylase (CYP11B1) activity (IC<sub>50</sub> = 7.83 <span class='symbol'>μ</span>M). Also inhibits CYP3A4 and cytochrome P450-mediated <span class='symbol'>ω</span>/<span class='symbol'>ω</span>-1 hydroxylase activity.
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