Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 3089 - 3096 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7657 | ATC 0175 hydrochloride |
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Potent, selective and orally active melanin-concentrating hormone receptor 1 (MCH<sub>1</sub>) antagonist (IC<sub>50</sub> values are 13.5 and > 10000 nM for MCH1 and MCH2 receptors respectively). Exhibits anxiolytic and antidepressant activity in rodents. Also displays affinity for 5-HT<sub>2B</sub> and 5-HT<sub>1A</sub> receptors (IC<sub>50</sub> values are 9.66 and 16.9 nM respectively).
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| BCC7658 | SNAP 94847 hydrochloride |
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Potent melanin-concentrating hormone receptor 1 (MCH<sub>1</sub>) antagonist (K<sub>i</sub> = 2.2 nM, K<sub>D</sub> = 530 pM) that displays > 80-fold and > 500-fold selectivity over <span class='symbol'>α</span><sub>1A</sub> and D<sub>2</sub> receptors respectively. Increases neurogenesis in the dentate gyrus and decreases food-reinforced operant responding <em>in vivo</em>. Exhibits anxiolytic activity and is orally active.
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| BCC7659 | Biocytin |
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Versatile marker used in anterograde, retrograde and intracellular neuroanatomical investigations and in biotinidase assays. Displays high solubility in aqueous solutions and has a low molecular weight facilitating injection using micropipettes. Can be incorporated with a variety of avidin and streptavidin conjugates for detection by light, fluorescence or electron microscope.
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| BCC7660 | LY 393558 |
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Dual 5-HT<sub>1B/1D</sub> receptor antagonist (pK<sub>B</sub> values are 9.05 and 8.98 respectively) and 5-HT re-uptake inhibitor (pIC<sub>50</sub> = 8.48). Potently antagonizes terminal autoreceptor activity <em>in vitro</em> and increases extracellular 5-HT levels above those evoked by fluoxetine <em>in vivo</em>. Also acts as an antagonist at 5-HT<sub>2A</sub> and 5-HT<sub>2B</sub> receptors (pK<sub>i</sub> values are 7.29 and 7.35 respectively).
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| BCC7661 | NS 304 |
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Selective prostacyclin IP<sub>1</sub> receptor agonist (K<sub>i</sub> values are 260 and 2100 nM and for human and rat IP receptors, and >10 <span class='symbol'>μ</span>M for EP<sub>1-4</sub>, DP, FP, and TP receptors). Prodrug for the active form of MRE 26. Ameliorates vascular endothelial dysfunction and increases femoral skin blood flow in rats. Orally available.
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| BCC7662 | JNJ 28871063 hydrochloride |
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Potent and selective ErbB receptor family inhibitor (IC<sub>50</sub> values are 21, 22 and 38 nM for ErbB4, EGFR and ErbB2 respectively). Displays potent growth inhibition of human cancer cell lines overexpressing ErbB2 <em>in vitro</em> (IC<sub>50</sub> = 60 - 168 nM) and inhibits growth of human tumor xenografts <em>in vivo</em>. Brain penetrant and orally active.
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| BCC7663 | PSN 375963 hydrochloride |
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GPR119 receptor agonist (EC<sub>50</sub> values are 8.4 and 7.9 <span class='symbol'>μ</span>M at human and mouse receptors respectively). Displays similar potency to the endogenous ligand oleylethanolamide (OEA).
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| BCC7664 | PNU 177864 hydrochloride |
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Highly selective dopamine D<sub>3</sub> receptor antagonist. Induces phospholipidosis and exhibits antischizophrenic activity <em>in vivo</em>.
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