Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN4933 | Vindoline |
| Vindoline is a chemical precursor to vinblastine and exhibits antimitotic activity by inhibiting microtubule assembly, it also has anti-ulcer activity. Vindoline can enhance the glucose-stimulated insulin secretion (GSIS) in MIN6 cells with the EC50 value of 50.2uM; it has relaxant effects in isolated rat renal arteries, it can dilate renal arteries in vitro through one or more pathways including inhibition of calcium entry,TEA+-sensitive potassium channel or protein kinase pathways in vascular smooth muscle cells. | |
| BCN4936 | Horminone |
| 1. Horminone may inhibit the initial steps of protein synthesis. 2. After administration of plant extracts containing Horminone has possibility of toxic effect. 3. Horminone and tingenone can inhibit the in vitro growth of Trypanosoma cruzi, 30 microM drug concentration producing total inhibition of growth. 4. Horminone has antimicrobial activity, it can inhibit the protein synthesis in several types of bacteria. 5. Horminone displays marked concentration-dependent antiproliferative effects. | |
| BCN4937 | Taraxeryl acetate |
| 1. Taraxeryl acetate shows the significant antiviral activity against herpes simplex virus (type II). 2. Taraxeryl acetate has less effect on cell cycle arrest and apoptosis of AGS cells than taraxerol. 3. A. roxburghiana has antidiabetic activity, could be attributed due to PTP1B inhibition by its triterpene constituents, betulin, betulinic acid and Taraxeryl acetate. | |
| BCN4938 | beta-Hydroxypropiovanillone |
| 1. beta-Hydroxypropiovanillone, an achiral compound, which is further degraded by lignin degradation. 2. beta-Hydroxypropiovanillone shows tyrosinase inhibitory activities. | |
| BCN4939 | Griffipavixanthone |
| 1. Griffipavixanthone can inhibit tumor metastasis and proliferation via downregulation of the RAF pathway in esophageal cancer. 2. Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, it induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS production. | |
| BCN4941 | Eichlerialactone |
| 1. Eichlerialactone and ethyl eichlerianoate show antimycobacterial activity against mycobacterium tuberculosis H37Ra, with minimum inhibitory concentration in the range of 25–50ug/mL. 2. Eichlerialactone is weakly cytotoxic to a breast cancer (BC) cell line. 3. Eichlerialactone exhibits good antibacterial activity against both the Gram-positive pathogens. | |
| BCN4942 | Cinnamamide |
| 1. Cinnamamide, a non-lethal repellent, deters feeding by a wide range of avian species;cinnamamide has the potential for use against the commensal rodent Mus musculus in situations where use of lethal control methods could be hazardous (e.g. food stores). 2. Cinnamamide is an antitumor agent with low cytotoxicity acting on matrix metalloproteinase, and may serve as a lead compound in the development of antitumor drugs. 3. Cinnamamide and betaine cinnamamide have growth-regulating activity on wheat. | |
| BCN4946 | Erysubin A |
| 1. Erysubin A , wighteone, and lupalbigenin show promising cytotoxic effects toward HL-60 cells (IC50 4.3 ± 0.7 to 18.0 ± 1.7 uM). | |
