Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 3113 - 3120 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7681 | SR 11237 |
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Pan retinoid X receptor (RXR) agonist that is devoid of any RAR activity.
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| BCC7682 | YM 202074 |
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High affinity, selective metabotropic glutamate receptor type 1 (mGlu<sub>1</sub>) antagonist. Binds an allosteric site of the rat mGlu<sub>1</sub> receptor with a K<sub>i</sub> of 4.8 nM. Inhibits mGlu<sub>1</sub>-mediated inositol phosphates production (IC<sub>50</sub> = 8.6 nM in rat cerebellar granule cells). Neuroprotective <em>in vivo</em>.
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| BCC7683 | FAK Inhibitor 14 |
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Selective focal adhesion kinase (FAK) inhibitor that displays no significant activity at a range of other kinases including EGFR, PDGFR and IGF-RI. Prevents FAK autophosphorylation at Y397 (IC<sub>50</sub> = 1 <span class='symbol'>μ</span>M), promotes cell detachment and inhibits cell adhesion <em>in vitro</em>. Exhibits antiproliferative activity in a variety of human tumor cell lines <em>in vitro</em> and in breast cancer cells <em>in vivo</em>.
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| BCC7684 | DMPO |
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Water soluble nitric oxide spin trap; allows the measurement of oxygen-centered free radicals in biological systems at room temperature using electron spin resonance (ESR). Has a high reaction rate constant for superoxide and hydroxyl radicals, and distinguishes simultaneously among a variety of important biologically generated free radicals.
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| BCC7685 | Tris DBA |
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<em>N</em>-myristoyltransferase-1 (NMT-1) inhibitor that prevents activation of MAPK, PI 3-K and STAT3 signaling pathways. Exhibits antiproliferative activity against melanoma cells <em>in vitro</em> and <em>in vivo</em>. Also used as a cyclization catalyst.
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| BCC7686 | M40 |
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Potent, non-selective galanin receptor antagonist (K<sub>i</sub> values are 1.82 and 5.1 nM at GAL<sub>1</sub> and GAL<sub>2</sub> respectively) that inhibits galanin (1-29) binding in rat brain <em>in vitro</em> (IC<sub>50</sub> = 3 - 15 nM). Attenuates the antidepressant effects of fluoxetine and blocks galanin-induced food intake <em>in vivo</em>. Also exhibits weak partial agonist activity at peripheral GAL<sub>2</sub> receptors at doses > 100 nM.
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| BCC7687 | S 25585 |
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Potent neuropeptide Y (NPY) Y5 receptor antagonist (IC50 values are 5.4, > 1000, > 10 000 and > 10 000 nM at Y5, Y1, Y2 and Y4 receptors respectively) that displays no affinity for a wide range of other receptors. Does not produce a conditioned taste aversion, suppress sodium appetite or cause pica in rats. Significantly inhibits NPY-induced feeding but not through blockade of Y5 receptors.
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| BCC7688 | GSK 0660 |
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Selective PPAR<span class='symbol'>δ</span> antagonist (IC<sub>50</sub> values are 0.155, > 10 and <span class='symbol'>≥</span> 10 <span class='symbol'>μ</span>M at PPAR<span class='symbol'>δ</span>, PPAR<span class='symbol'>α</span> and PPAR<span class='symbol'>γ</span> respectively). Exhibits inverse agonist effects when administered by itself.
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