Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN5033 4-Nitrocinnamic acid
4-Nitrocinnamic acid is a photosensitive compound. 4-Nitrocinnamic acid has inhibitory effects on tyrosinase.
BCN5034 4-Methylcinnamic acid
4-Methylcinnamic acid is a photosensitive compound.
BCN1534 trans-4-(Trifluoromethyl)cinnamic acid
trans-4-(Trifluoromethyl)cinnamic acid is a photosensitive compound.
BCN5036 2-Chlorocinnamic acid
2-Chlorocinnamic acid is a photosensitive compound, it can inhibit tyrosinase activity. 2-Chlorocinnamic acid and 4-chlorocinnamic acid show potent urease inhibitory activities with the respective IC50 values of 0.66 and 1.10 uM.
BCN5037 4-Methoxycinnamic acid
4-Methoxycinnamic acid is a photosensitive compound, it shows various pharmacologic actions such as anti-cancer, hepatoprotective and antihyperglycemic activities, it also can stimulate insulin secretion from pancreatic β-cells by increasing Ca2+ influx via the L-type Ca2+ channels, but not through the closure of ATP-sensitive K+ channels. 4-Methoxycinnamic acid can strongly inhibit the diphenolase activity of mushroom tyrosinase, with the IC 50 value of 0.42 mM, and the inhibition is reversible.
BCN5038 2-Methoxycinnamic acid
2-Methoxycinnamic acid is a photosensitive compound. 2-Methoxycinnamic acid can enhance inhibition of tyrosinase activity.
BCN5039 2-Hydroxycinnamic acid
2-Hydroxycinnamic acid has photooxidant activity; 2-hydroxycinnamic acid germanium has strong inhibitory effect on the tumor U14; trans-2-hydroxycinnamic acid has efficacy against trichlorfon-induced oxidative stress in wistar rats.
BCN5040 3,4-Dimethoxycinnamic acid
3,4-Dimethoxycinnamic acid is a bioavailable coffee component as a perspective anti-prion compound and bind potently to prion protein with a Kd of 405 nM.