Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN5049 | Cytochalasin D |
| 1. Cytochalasin D-induced extension of neurite-like processes might correlate with enhanced accumulation of PrPres. 2. Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. 3. Cytochalasin D inhibits CT26 tumor growth potentially through inhibition of cell proliferation, induction of cell apoptosis and suppression of tumor angiogenesis. 4. Cytochalasin D stimulates the expression of TF in B16 melanoma cells, activating both coagulation-dependent and -independent pathways via binding to FVIIa, eventually promoting lung metastasis. 5. Cytochalasin D inhibits smooth muscle contraction by directly inhibiting contractile apparatus. 6. Cytochalasin D is an inhibitor of microfilament-dependent phagocytosis, it (0.5 or 1.0 micrograms/ml) can inhibit intracellular multiplication of L. pneumophila in U937 monocytes. 7. Cytochalasin D may be an inhibitor of some fertilization processes such as sperm penetration or sperm head decondensation. | |
| BCN5050 | 11-Hydroxytabersonine |
| 1. 11-Hydroxytabersonine has antitumor activety. | |
| BCN5051 | Stigmastane-3,6-dione |
| 1. Stigmastane-3,6-dione has anti-inflammatory activity. 2. 5 alpha-Stigmastane-3,6-dione shows antifeedant activity against bell weevils. | |
| BCN5052 | 2,6-Dimethoxy-1-acetonylquinol |
| 1. 2,6-Dimethoxy-1-acetonylquinol shows varying degrees of in vitro antimalarial activity against Plasmodium falciparum. 2. 2,6-Dimethoxy-1-acetonylquinol is devoid of significant cytotoxicity to the human oral epidermoid KB cancer cell line. | |
| BCN5053 | Conocarpan |
| 1. Conocarpan has antinociceptive effects. 2. Conocarpan is quite active against S. aureus and B. subtilis with MIC of 6.25 micrograms/ml, it also shows activity against M. tuberculosis (MIC=15.6 ug/ml). 3. Conocarpan shows considerable activity against epimastigote forms of T. cruzi, with 50% inhibition concentrations (IC50) of 8.0 microg/ml. | |
| BCN5054 | Methyl 6-hydroxyangolensate |
| 1. Methyl 6-hydroxyangolensate shows antifungal and antibacterial activities. | |
| BCN5055 | alpha-Amyrin palmitate |
| 1. alpha-Amyrin palmitate is antiarthritic in the adjuvant model of arthritis in rats. 2. alpha-Amyrin palmitate is a potent non-competitive inhibitor of chymotrypsin (Ki=6 microM). 3. alpha Amyrin palmitate shows weak cytotoxicity against the A2780 human ovarian cancer cell line. | |
| BCN5056 | Guaijaverin |
| Guaijaverin is a urease inhibitor, it (IC(50)=0.18 microM) shows an inhibitory effect on rat lens aldose reductase. Guaijaverin has antioxidant, hypoglycemic activity and inhibitory capacity against free fatty acid release.It demonstrates high potential antiplaque agent by inhibiting the growth of the Strep. Mutans. | |
