Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 3233 - 3240 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7804 | NF 546 |
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P2Y11 agonist (pEC50 = 6.27). Exhibits selectivity for P2Y11 over a range of P2Y and P2X receptors.
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| BCC7805 | SF 11 |
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NPY Y<sub>2</sub> antagonist (IC<sub>50</sub> = 199 nM). Displays no affinity for Y<sub>1</sub> receptor at concentrations up to 35 <span class='symbol'>μ</span>M. Causes significant lethality in mice. Brain penetrant.
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| BCC7806 | JNJ 303 |
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Potent I<sub>Ks</sub> blocker (IC<sub>50</sub> = 64 nM). Displays no effects on other cardiac channels; IC<sub>50</sub> values are 3.3, >10, 11.1 and 12.6 <span class='symbol'>μ</span>M for I<sub>Na</sub>, I<sub>Ca</sub>, I<sub>to</sub> and I<sub>Kr</sub> currents respectively. Prolongs QT and causes unprovoked torsades de pointes (TdP).
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| BCC7807 | WAY 208466 dihydrochloride |
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High affinity, selective 5-HT6 agonist (EC50 = 7.3 nM at the human 5-HT6 receptor). Elevates cortical GABA levels in vivo in rat frontal cortex. Exhibits antidepressant and anxiolytic-like effects.
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| BCC7808 | NAADP tetrasodium salt |
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Ca2+ mobilizing agent. Initiates Ca2+ release via type 1 ryanodine receptor (RyR1) activation. Also regulates Ca2+ release from intracellular stores distinct from the endoplasmic reticulum (ER); displays affinity for two-pore channels (TPCs) which release Ca2+ from acidic organelles.
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| BCC7809 | SC 236 |
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Selective COX-2 inhibitor (IC<sub>50</sub> values are 0.005 and 17.8 <span class='symbol'>μ</span>M for COX-2 and COX-1 respectively). Displays anti-inflammatory properties and potent antimetastatic activity against both experimental metastases and spontaneous metastases arising following primary tumor excision.
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| BCC7810 | NIDA 41020 |
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High affinity CB1 receptor antagonist (Ki = 4.1 nM). Exhibits significantly reduced lipophilicity compared to other CB1 antagonists.
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| BCC7811 | PF 998425 |
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Selective non-steroidal androgen receptor (AR) antagonist (IC<sub>50</sub> values are 26 nM and 90 nM in AR binding assays and cellular assays respectively). Displays low affinity for progesterone receptor (IC<sub>50</sub> > 10 <span class='symbol'>μ</span>M). Active <em>in vivo</em>.
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