Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN5130 | Velutin |
| Velutin has strong anti-inflammatory activity, it can effectively inhibit the expression of proinflammatory cytokines TNF-α and IL-6 in low micromole levels by inhibiting NF-κB activation and p38 and JNK phosphorylation. Velutin controls HIF-1α activity during PgLPS-activated osteoclastogenesis probably through modulation of the NF-κB pathway, perhaps it could be used therapeutically to prevent bone loss seen in periodontitis.Velutin can induce apoptosis in tumor cells. | |
| BCN5136 | Picrasin B |
| 1. Picrasin B shows a significant clastogenic activity in cell cultures of Don lung cells of Chinese hamster. | |
| BCN5138 | Foliamenthoic acid |
| 1. Foliamenthoic acid shows α-glucosidase inhibition. | |
| BCN5139 | 2,3',4,6-Tetrahydroxybenzophenone |
| 1. 2,3',4,6-Tetrahydroxybenzophenone possesses significant antioxidant activity. | |
| BCN5141 | 22-Dehydroclerosterol |
| 1. 22-Dehydroclerosterol has antibacterial activity against against E. coli, S. aureus, and H. pylori. | |
| BCN5142 | 6',7'-Dihydroxybergamottin |
| 6',7'-Dihydroxybergamottin(DHB), a well-known inhibitor of CYP3A4, the inhibition of CYP3A4 activity by DHB includes the inhibition of POR activity, DHB can inhibit nifedipine oxidation in a concentration-dependent manner. | |
| BCN5145 | 2,3-Dihydroxy-12-oleanen-28-oic acid |
| 1. 2,3-Dihydroxy-olean-12-en-28-oic acids show a low cytotoxicity towards several human tumor cell lines. | |
| BCN5148 | Crenatine |
| 1. Crenatine possesses antibacterial activity, it is more effective against Gram-positive than Gram-negative bacteria. | |
