Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 3273 - 3280 of 9359 hot products
| Catalog No. | Product Name |
|---|---|
| BCC7844 | Ralfinamide mesylate |
|
Sodium channel blocker. Suppresses tetrodotoxin (TTX)-resistant Na+ currents approximately twice as selectively as TTX-sensitive currents. Antinociceptive; displays analgesic effects in animal models of inflammatory and neuropathic pain.
|
|
| BCC7845 | Org 24598 lithium salt |
|
Selective inhibitor of the glial glycine transporter (GlyT1) (pIC50 values are 6.9, <4 and <3 for GlyT1, GABA transporter and Glyt2 respectively).
|
|
| BCC7846 | PT 1 |
|
AMP-activated protein kinase (AMPK) activator. Stimulates AMPK heterotrimer (<span class='symbol'>α</span>1<span class='symbol'>β</span>1<span class='symbol'>γ</span>1) activity (EC<sub>50</sub> = 0.3 <span class='symbol'>μ</span>M). Selectively increases the activity of <span class='symbol'>γ</span>1- but not <span class='symbol'>γ</span>3-containing complexes. Thought to directly activate AMPK by antagonizing autoinhibition.
|
|
| BCC7847 | Sipatrigine |
|
Blocker of voltage-dependent sodium channels (Na<sub>V</sub>). Inhibits glutamate release; displays neuroprotective activity in rat models of cerebral ischemia. Also thought to block Ca<sup>2+</sup> channels. Analog of lamotrigine.
|
|
| BCC7848 | AC 261066 |
|
Potent RAR<span class='symbol'>β</span>2 agonist (pEC<sub>50</sub> = 8.1). Selective over RAR<span class='symbol'>β</span>1, RAR<span class='symbol'>α</span> and RAR<span class='symbol'>γ</span> (pEC<sub>50</sub> values are 6.4, 6.2 and 6.3 respectively). More potent and orally available than AC 55649.
|
|
| BCC7849 | BINA |
|
Selective positive allosteric modulator of mGlu2 (EC50 = 33.2 nM in CHO cells expressing human mGlu2). Displays no effect on glutamate-induced activation of other mGlu receptor subtypes. Exhibits antipsychotic and anxiolytic properties in mice.
|
|
| BCC7850 | BMS 470539 dihydrochloride |
|
Potent, selective melanocortin MC1 receptor agonist (IC50 = 120 nM). Exhibits anti-inflammatory properties following ischemia-reperfusion in the vasculature. Inhibits leukocyte trafficking.
|
|
| BCC7851 | Flupenthixol dihydrochloride |
|
Antipsychotic drug. Exhibits antagonistic activity at dopamine D1-5 receptors. Used in schizophrenia treatment.
|
|