Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 3321 - 3328 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7893 | OctMAB |
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Dynamin inhibitor (IC50 = 1.9 μM for dynamin I). Inhibits receptor-mediated endocytosis (IC50 = 16 μM). Displays similar activity to MitMAB .
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| BCC7894 | RWJ 50271 |
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Selective inhibitor of LFA-1 (lymphocyte function-associated antigen-1) adhesion to soluble intercellular adhesion molecule (sICAM) (IC<sub>50</sub> = 5 <span class='symbol'>μ</span>M in HL60 cells).
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| BCC7895 | NPEC-caged-D-AP5 |
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D-AP5 caged with the photosensitive 1-(2-nitrophenyl)ethoxycarbonyl (NPEC) group. NMDA receptor antagonist.
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| BCC7896 | TQS |
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Type II positive allosteric modulator of <span class='symbol'>α</span>7 nACh receptors (pEC<sub>50</sub> = 5.5). Displays no agonist activity at <span class='symbol'>α</span>7 receptors at concentrations up to 0.1 mM; potentiates agonist-evoked responses and reduces rate of desensitization of <span class='symbol'>α</span>7 nAChRs. Exhibits potency and efficacy similar to PNU 120596.
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| BCC7897 | GW 803430 |
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Selective melanin-concentrating hormone receptor 1 (MCH1) antagonist (IC50 = 9.3 nM). Displays antiobesity and antidepressant-like effects in rats and mice. Orally active.
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| BCC7898 | A 887826 |
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Potent voltage-dependent NaV1.8 channel blocker (IC50 = 11 nM in recombinant human NaV1.8 channels). Reduces tactile allodynia in neuropathic rat models. 3- and 28-fold more potent at NaV1.8 channels compared to NaV1.2 and NaV1.7 channels respectively.
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| BCC7899 | TMPyP4 tosylate |
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Cationic porphyrin; inhibits human telomerase. Stacks with G tetrads to stabilize quadruplex DNA. Inhibits cell proliferation and induces cell death in three myeloma cell lines. Activity results in telomere shortening at concentrations between 1 and 5 <span class='symbol'>μ</span>M.
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| BCC7901 | TCN 238 |
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Positive allosteric modulator of mGlu<sub>4</sub> receptors (EC<sub>50</sub> = 1.0 <span class='symbol'>μ</span>M for human and rat mGlu<sub>4</sub> receptors). Orally available and brain penetrant.
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