Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 3345 - 3352 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7918 | Phosphocreatine disodium salt |
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Phosphate reservoir; used to regenerate ATP during skeletal muscle contraction.
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| BCC7919 | ST 1936 oxalate |
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High affinity, selective agonist of 5-HT<sub>6</sub> receptors (K<sub>i</sub> values are 13, 168, and 245 nM for human 5-HT<sub>6</sub>, 5-HT<sub>7</sub> and 5-HT<sub>2B</sub> receptors respectively). Displays moderate affinity for human <span class='symbol'>α</span><sub>2</sub> adrenergic receptors (K<sub>i</sub> = 300 nM). Shown to increase Ca<sup>2+</sup> concentration and phosphorylation of Fyn kinase, and regulate the activation of ERK1/2 in cloned cells.
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| BCC7920 | A 582941 |
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Selective <span class='symbol'>α</span>7 nAChR partial agonist; exhibits high affinity for both rat and human <span class='symbol'>α</span>7 receptors (K<sub>i</sub> values are 10.8 and 16.7 nM respectively). Displays ~15-fold selectivity for <span class='symbol'>α</span>7 over 5-HT<sub>3</sub> receptors (K<sub>i</sub> = 150 nM for 5-HT<sub>3</sub>).
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| BCC7921 | Ro 67-4853 |
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Positive allosteric modulator of mGlu group I receptors (pEC50 value is 7.16 for the rat mGlu1a receptor). Exhibits activity at all group I receptors, including human and rat mGlu1 and rat mGlu5. Enhances the effects of (S)-DHPG in CA3 neurons (EC50 = 95 nM).
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| BCC7922 | Ro 01-6128 |
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Positive allosteric modulator of mGlu1 receptors. Potentiates glutamate-induced calcium release (EC50 = 104.2 nM at rat mGluR1a).
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| BCC7923 | JHW 007 hydrochloride |
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Dopamine uptake inhibitor; displays high affinity for the dopamine transporter (DAT) (Ki = 25 nM compared to 1330 and 1730 for NET and SERT respectively). Suppresses the effects of cocaine administration in a dose-dependent manner and decreases cocaine and methamphetamine self-administration in rats.
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| BCC7924 | Talsupram hydrochloride |
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Selective noradrenalin re-uptake inhibitor; exhibits a high affinity for the human noradrenalin transporter (NET) against SERT and DAT (IC50 values are 0.79, 850 and 9300 nM for inhibition of monoamine uptake by NET, SERT and DAT respectively). Antidepressant.
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| BCC7925 | Bicifadine hydrochloride |
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Potent antagonist of the noradrenalin transporter (IC50 = 55 nM); also displays antagonist activity at the 5-HT and dopamine transporters (IC50 values are 117 nM and 910 nM respectively). Orally active. Exhibits antinociceptive and antiallodynic activity in rodent models of acute, persistent, and chronic pain.
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