Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN5336 Eleutheroside D
Eleutheroside has protective effect to myocardial ischemic-reperfusion injury(IRI) in isolated rats.
BCN5337 Tricine
Tricine can clearly visualize tumors, may as melanoma imaging agents. Using the combination of tricine and a phosphine ligand, HYNIC-derivatized peptides or other small molecules can be labeled with 99mTc in high specific activity and with high stability for potential use as radiopharmaceuticals.
BCN5338 Luteolin-7-O-glucuronide
Luteolin-7-O-glucuronide has anti-inflammatory activity. Luteolin 7-O-glucuronide shows potent α-glucosidase inhibitory effect with IC50 values of 14.7 uM, it also exhibits moderate α-amylase activity with IC50 values 61.5uM.Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively.
BCN5339 Quetiapine fumarate
1. Quetiapine fumarate monotherapy (150 mg/day and 300 mg/day) is effective, with safety and tolerability in the treatment of patients with major depressive disorder. 2. Quetiapine fumarate can treat patients with schizophrenia.
BCN5341 7-Xylosyltaxol
7-xylosyltaxol is a taxol (Paclitaxel) derivative, has antineoplastic activity.
BCN1592 N-Debenzoyl-N-(tert-butoxycarbonyl)taxol
1. 10-Acetyldocetaxel(N-Debenzoyl-N-(tert-butoxycarbonyl)taxol ) has selective high-activity and high-efficiency functions on treating metastatic colon cancer and stomach cancer.
BCN5342 Docetaxel
Docetaxel is an antineoplastic drug by inhibiting microtubule depolymerization, and attenuating of the effects of bcl-2 and bcl-xL gene expression.
BCN5343 Cephalomannine
Cephalomannine is a taxol derivative with antitumor, antiproliferative properties, it shows cytotoxicity in human glial and neuroblastoma cell-lines.