Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 3425 - 3432 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7999 | SR 3576 |
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Highly potent and selective JNK3 inhibitor (IC50 = 7 nM); exhibits > 2800-fold selectivity over p38.
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| BCC8000 | L002 |
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p300 inhibitor (IC<sub>50</sub> = 1.98 <span class='symbol'>μ</span>M). Inhibits histone and p53 acetylation, and suppresses STAT3 activation in cell-based assays. Also suppresses tumor growth in a mouse MDA-MB-468 xenograft model.
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| BCC8001 | YZ9 |
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PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor (IC<sub>50</sub> = 0.183 <span class='symbol'>μ</span>M). Also competitively inhibits F-6-P (K<sub>i</sub> = 0.094 <span class='symbol'>μ</span>M). Inhibits cell growth (GI<sub>50</sub> = 2.7 <span class='symbol'>μ</span>M) in a XTT-based <em>in vitro</em> toxicology assay.
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| BCC8002 | BIO 5192 |
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Highly selective and potent inhibitor of integrin <span class='symbol'>α</span><sub>4</sub><span class='symbol'>β</span><sub>1</sub> (Very Late Antigen-4; VLA-4) (K<sub>d</sub> < 10 pM). Selectively binds <span class='symbol'>α</span><sub>4</sub><span class='symbol'>β</span><sub>1</sub> over a range of other integrins (IC<sub>50</sub> values are 1.8, 138, 1053, > 500 and > 10,000 nM for <span class='symbol'>α</span><sub>4</sub><span class='symbol'>β</span><sub>1</sub>, <span class='symbol'>α</span><sub>9</sub><span class='symbol'>β</span><sub>1</sub>, <span class='symbol'>α</span><sub>2</sub><span class='symbol'>β</span><sub>1</sub>, <span class='symbol'>α</span><sub>4</sub><span class='symbol'>β</span><sub>7</sub> and <span class='symbol'>α</span><sub>IIb</sub><span class='symbol'>β</span><sub>3</sub>, respectively). Induces a 30-fold increase in mobilization of murine hematopoietic stem and progenitor cells; displays a 3-fold additive effect with AMD 3100.
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| BCC8003 | NKY 80 |
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Inhibitor of adenylyl cyclase (AC). Exhibits greater affinity for AC5 over AC3 and AC2 (IC<sub>50</sub> values are 8.3 <span class='symbol'>μ</span>M, 132 <span class='symbol'>μ</span>M and 1.7 mM respectively).
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| BCC8004 | SZL P1-41 |
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Skp2 inhibitor; thought to prevent assembly of Skp2-Skp1 complexes. Selectively suppresses Skp2 SCF E3 ligase activity but exhibits no effect on the activity of other SCF complexes. Also inhibits Skp2-mediated p27 and Akt ubiquitination in vivo and in vitro. Suppresses the survival of cancer cells and cancer stem cells by triggering cell senescence and inhibiting glycolysis. Exhibits antitumor effects in multiple animal models and cancer cell lines.
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| BCC8005 | PA 452 |
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RXR antagonist (pA2 = 7.11). Triggers dissociation of RXR tetramers. Attenuates cell proliferation and induces apoptosis in MCF-7 breast cancer cells.
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| BCC8006 | Acridine Orange hydrochloride |
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Cell and organelle membrane permeable nucleic acid binding dye. Emits green fluorescence when bound to double stranded DNA and red fluorescence when bound to RNA or single stranded DNA. Used in cell cycle and apoptosis studies and as a lysosomal dye.
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