Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN5425 | Naringenin triacetate |
| 1. Naringenin triacetate exhibits a better binding affinity with multiple crystal structures of first bromodomain BRD4 (BRD4 BD1) when compared with the known inhibitors. | |
| BCN5426 | Murrangatin |
| 1. Murrangatin and murracarpin show chondroprotective activity by downregulation of interleukin-1β, tumor necrosis factorα, prostaglandins E2,and matrix metalloproteinases -13, and both of them may be a new backbone for developing inhibitors of cyclooxygenase 2. 2. Murrangatin can significantly inhibit Epstein–Barr virus early antigen (EBV–EA) activation, and preserve the high viability of Raji cells, suggests that it may be a valuable anti-tumor-promoting agent. 3. Murrangatin exhibits cytotoxicity against cholangiocarcinoma cell line, KKU-100. 4. Murrangatin exhibits antibacterial activity against P. gingivalis (ATCC 33277). 5. Murrangatin shows soluble epoxide hydrolase inhibitory activity with IC50 values 13.9±6.5uM. | |
| BCN5427 | Wilforgine |
| Wilforgine exhibits insecticidal activity of some degree. | |
| BCN5428 | 7,4'-Dihydroxy-3'-prenylflavan |
| 1. 7,4'-Dihydroxy-3'-prenylflavan has antibacterial activity. | |
| BCN5430 | Dehydroabietinol |
| 1. Dehydroabietinol inhibits growth of chloroquine-sensitive as well as chloroquine-resistant strains of Plasmodium falciparum cultivated in erythrocytes in vitro (IC 50 26-27 microM). | |
| BCN5431 | Totaradiol |
| 1. Totaradiol shows antioxidant activity, it can inhibit linoleic acid autoxidation but not generation of superoxide anion. 2. Totaradiol exhibits cytotoxic activity against the A2780 ovarian cancer cell line. | |
| BCN5432 | Phaseollidin |
| 1. Phaseollidin, a phytoalexin from Phaseolus vulgaris, has antimicrobial activity. 2. Phaseollidin has anti-anxiety properties. | |
| BCN5433 | Cimifugin |
| Cimifugin evidently inhibits FITC-induced type 2 allergic contact dermatitis,and its mechanism might related to regulating the balance of Th1 /Th2 by inhibiting type 2 cytokines. Cimifugin displayed low to moderate inhibition towards AChE and BChE (3.12 and 21.63%, respectively) at 200 ug/mL. | |
