Hot Natural Products & Bioactive Compounds

BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.

Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.

Hot Products from BioCrick

Showing 3473 - 3480 of 9359 hot products

BioCrick hot natural products and bioactive compounds
Catalog No. Product Name
BCC8053 GSK2194069
Potent human fatty acid synthase (hFASN) inhibitor (IC<sub>50</sub> = 7.7 nM); inhibits hFAS <span class='symbol'>&#946;</span>-ketoacyl reductase activity. Inhibits lipid synthesis and attenuates proliferation of A549 non-small-cell lung cancer cells (EC<sub>50</sub> = 15 nM) <em>in vitro</em>.
BCC8056 NIBR189
Potent and selective EBI2 (GPR183) receptor antagonist (IC50 values are 11 and 15 nM for human and mouse EBI2 receptors respectively). Exhibits selectivity for EBI2 over a panel of other receptors, enzymes and transporters. Blocks oxysterol-induced migration of U937 monocyte cells. Orally bioavailable.
BCC8063 ML365
Potent and selective TASK-1 (K2P3.1/KCNK3) channel blocker (IC50 values are 4 and 390 nM at TASK-1 and TASK-3, respectively). Displays little or no inhibition at Kir2.1, voltage-gated potassium channels, KCNQ2 and KV11.1 (hERG).
BCC8071 Valifenalate
Valifenalate(IR5885; Valiphenal), which is approved for application on high-value crops such as grapes, tomatoes and other vegetables, is effective against various types of mildew and is currently marketed primarily under the Valis moniker; insecticide agent.
BCC8072 Penthiopyrad
Penthiopyrad(MTF-753) is a carboxamide fungicide used to control a broad spectrum of diseases on large variety of corps; inhibits fungal respiration by binding to mitochondrial respiratory complex II.
BCC8073 Pyraclonil
Pyraclonil is a herbicide agent.
BCC8077 SB 225002
Potent and selective CXCR2 chemokine receptor antagonist (IC<sub>50</sub> = 22 nM) that displays &gt; 150-fold selectivity over CXCR1 receptors. Causes inhibition of IL-8 and GRO<span class='symbol'>&alpha;</span>-mediated calcium mobilization in HL60 cells (IC<sub>50</sub> values are 8 and 10 nM respectively). Prevents IL-8-induced neutrophil chemotaxis <em>in vitro</em> and sequestration <em>in vivo</em>. Inhibits HIV replication in lymphocytes and macrophages.
BCC8078 8-Bromo-cAMP, sodium salt
Cell-permeable cAMP analog; activator of protein kinase A. Also available as part of the PKA.