Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 3481 - 3488 of 9359 hot products
| Catalog No. | Product Name |
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| BCC8079 | Dibutyryl-cAMP, sodium salt |
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Cell-permeable analog of cAMP; activates cAMP-dependent protein kinases. Promotes differentiation of dopaminergic neurons (iDA) from hPSCs in combination with other reagents.
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| BCC8080 | KT 5720 |
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Potent, selective inhibitor of protein kinase A (K<sub>i</sub> = 60 nM). Has no effect on PKG or PKC (K<sub>i</sub> > 2 <span class='symbol'>μ</span>M). Reversibly arrests human skin fibroblasts in the G<sub>1</sub> phase.
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| BCC8081 | cAMPS-Sp, triethylammonium salt |
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Cell-permeable cAMP analog that activates cAMP receptor proteins such as PKA and cAMP-regulated guanine nucleotide exchange factor. Enantiomer cAMPS-Rp, triethylammonium salt also available.
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| BCC8082 | cAMPS-Rp, triethylammonium salt |
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Cell-permeable cAMP analog; acts as a competitive antagonist of cAMP-induced activation of PKA (IC<sub>50</sub> = 11 - 16 <span class='symbol'>μ</span>M) by interacting with cAMP binding sites on the regulatory subunits. Resistant to hydrolysis by phosphodiesterases. Enantiomer cAMPS-Sp, triethylammonium salt also available.
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| BCC8083 | RHC 80267 |
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Inhibitor of diacylglycerol lipase (IC<sub>50</sub> values are 1.1 and 4 <span class='symbol'>μ</span>M in rat cardiac myocytes and canine platelets respectively). Weakly inhibits phospholipases C and A<sub>2</sub>. Potentiates acetylcholine evoked relaxation in mesenteric arteries by the inhibition of cholinesterase activity (IC<sub>50</sub> = 4 <span class='symbol'>μ</span>M).
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| BCC8084 | cGMP Dependent Kinase Inhibitor Peptide |
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Competitive inhibitor of cGMP-dependent protein kinase (PKG); analog of a substrate peptide corresponding to a phosphorylation site of histone H2B. Competes with synthetic substrates (Ki = 86 mM) but does not inhibit phosphorylation of intact histones by PKG. Inhibits phosphorylation of intact histones by PKA.
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| BCC8085 | c-JUN peptide |
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Peptide comprising residues 33 - 57 of the JNK binding (<span class='symbol'>δ</span>) domain of human c-Jun. Disrupts JNK/c-Jun interaction leading to inhibition of serum-induced c-Jun phosphorylation, up-regulation of p21<sup>cip/waf</sup> and modulation of inflammatory gene expression. Specifically induces apoptosis in HeLa tumor cells.
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| BCC8086 | SL 0101-1 |
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Selective inhibitor of ribosomal S6 kinase (RSK) (IC50 = 89 nM for RSK2). Does not inhibit upstream kinases such as MEK, Raf and PKC. Inhibits the growth of MCF-7 human breast cancer cells with no effect on the normal breast cell line.
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