Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN5437 | Naringenin trimethyl ether |
| Naringenin trimethyl ether shows significant molluscicidal activity with a median lethal concentration (LC(50)) of 3.9 μg/mL. | |
| BCN5439 | Seneciphylline N-oxide |
| 1. Seneciphylline N-oxide and senecionine N-oxide are probably tumorigenic due to their potential conversion into seneciphylline and senecionine via metabolic reduction in the body. | |
| BCN5441 | Isovitexin |
| Isovitexin, a food phytochemical contained in dietary rice products, it exhibits in vivo α-glucosidase inhibition, it possesses antihyperglycemic, neuroprotective, anti-inflammatory and anti-oxidant activities. Isovitexin inhibited xanthine oxidase with an IC50 value of 15.2 microM, it may protect cells from oxidative stress. It inhibited JNK, MAPK and NF-κB and activated HO-1/Nrf2 pathways. | |
| BCN5442 | 2'-O-Methylperlatolic acid |
| 1. 2'-O-Methylperlatolic acid and confluentic acid are monoamine oxidase B inhibitors in a Brazilian plant, Himatanthus sucuuba. | |
| BCN5443 | Gelsevirine |
| 1. Gelsevirine has anxiolytic activity, may be via the agonist action of glycine receptor in the brain. 2. Gelsevirine can significantly inhibit the proliferation of human carcinoma cell line SW480 and MGC80-3 in a dose-dependent manner, the 50% inhibiting concentration(IC50)of gelsevirine on SW480 cells and MGC80-3 cells are 1.41±0.06 mM and 1.22±0.11 mM respectively. | |
| BCN5444 | Nuezhenide |
| Nuezhenide is the main inhibitory compound of fruits, it shows a clear inhibitory effect to the seeds of wheat and Chinese cabbage. It significantly protects human neuroblastoma SH-SY5Y cells from 6-hydroxydopamine-induced neurotoxicity. | |
| BCN5447 | Buxbodine B |
| 1. Buxbodine B has weak anti-AChE activity with IC50 values in the range of 10.8-98μM. | |
| BCN5449 | Kamebanin |
| 1. Kamebanin, a natural diterpenoid, has antibacterial activity. 2. Kamebanin shows efficient cytotoxic activity against HeLa and HL-60 cells. | |
