Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN5314 | 2',4'-Dihydroxy-6'-methoxyacetophenone |
| 2,4-Dihydroxy-6-methoxyacetophenone exhibits a moderate antispasmodic activity. | |
| BCN5315 | Alpinetin |
| Alpinetin has antibacterial, anti-inflammatory, and anti-cancer activities; it inhibits proliferation ,regulates of the Bcl-2 family and XIAP expression, releases of cytochrome c and activates caspases. | |
| BCN5318 | 3'-O-Methylorobol |
| 1. 3'-O-Methylorobol can increase osteoblast differentiation. 2. 3'-O-Methylorobol exerts potential analgesic properties. 3. 3'-O-Methylorobol exhibites moderate antioxidant activity in the 2,2-diphenyl-1-picrylhydrazyl free radical scavenging assay. | |
| BCN5319 | Jatrorrhizine |
| Jatrorrhizine has neuroprotective, antioxidative, anti-inflammatory, antihypercholesterolemic, and anti-hyperglycemia effects.Jatrorrhizine is expected to be developed as a new gastric prokinetic drug, it is metabolized by human CYP1A2 and multiple UGT1A isoforms. It has inhibitory activities against the expression of inducible NO syntase (iNOS) and cyclooxygenase-2 (COX-2), and can improve the utilization and excretion of cholesterol by up-regulating the mRNA and protein expression of LDLR and CYP7A1. | |
| BCN5321 | 6-Hydroxystigmasta-4,22-dien-3-one |
| 1. 6β-Hydroxystigmasta-4,22-dien-3-one exhibits in vitro antibacterial activity. 2. 6β-Hydroxystigmasta-4,22-dien-3-one shows antioxidant activity, the value of IC50 toward DPPH is 233.4 ± 0.28 uM. | |
| BCN5324 | beta-Costic acid |
| 1. The use of costic acid and other components from the plant Dittrichia viscosa (Greek: aconiza) and related species for the preparation of acaricidal products used against the acari Varroa destructor as parasite of the honey bee. | |
| BCN5325 | Serpentinine |
| 1. Serpentinine may have antihypertensive effect. | |
| BCN5326 | Apigenin-7-glucuronide |
| Apigenin-7-glucuronide possesses multiple pharmacological activities, including anti-oxidant, anti-complement, anti-inflammatory, and aldose reductase inhibitory activities, it can inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 12.87, 22.39, 17.52, 0.27 μM for MMP-3, MMP-8, MMP-9, MMP-13, respectively. Apigenin 7-O-β-D-glucuronide protects mice from LPS-induced endotoxin shock by inhibiting proinflammatory cytokine production, it may be used as a dietary complement for health promotion. | |
