Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 3313 - 3320 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7884 | HA 130 |
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Potent and selective autotaxin inhibitor (IC50 = 28 nM). Binds and inhibits autotaxin reversibly. Displays no activity against the proteasome, recombinant NPP1 or alkaline phosphatase. Inhibits ATX-mediated cell migration in an A2058 melanoma cell assay.
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| BCC7885 | IEM 1925 dihydrobromide |
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Voltage- and use-dependent open-channel antagonist of AMPA receptors. Selective between subtypes; blocks GluR2 subunit-lacking receptors more potently than GluR2-containing receptors (K<sub>D</sub> for GluR2-containing AMPAR is 210 times higher at -80 mV). More potent than IEM 1460 and IEM 1754 due to a slower unblocking rate. Alleviates inflammatory pain in a rat model of peripheral inflammation.
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| BCC7886 | BTZO 1 |
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Macrophage migration inhibitory factor (MIF) binder (Kd = 68.6 nM). Activates antioxidant response element (ARE)-mediated gene expression. Suppresses oxidative stress-induced cardiomyocyte apoptosis in vitro. Cardioprotective.
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| BCC7887 | SB 277011A dihydrochloride |
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Selective dopamine D3 receptor antagonist (pKi values are 8.0, 6.0, 5.0 and <5.2 for D3, D2, 5-HT1D and 5-HT1B respectively). Brain penetrant.
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| BCC7888 | EMDT oxalate |
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Selective 5-HT6 agonist (with a Ki value of 16 nM at human 5-HT6 receptors). Exhibits potency comparable to serotonin for the activation of adenylate cyclase. Displays antidepressant-like effects.
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| BCC7889 | Prostaglandin F2α |
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Prostaglandin E<sub>2</sub> and F<sub>2<span class='symbol'>α</span></sub> receptor agonist. Naturally-occurring prostaglandin and potent vasoconstrictor. Induces cardiomyocyte hypertrophy <em>in vitro</em>. Exhibits luteolytic activity.
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| BCC7890 | XCC |
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Adenosine receptor antagonist (Ki values are 42, 68 and 1130 nM for A1, A2B and A2A receptors).
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| BCC7891 | Dynole 34-2 |
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Dynamin I inhibitor (IC<sub>50</sub> = 1.3 <span class='symbol'>μ</span>M). Inhibits receptor-mediated endocytosis (RME) (IC<sub>50</sub> = 5.0 <span class='symbol'>μ</span>M).
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