Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 3265 - 3272 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7836 | NPEC-caged-serotonin |
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NPEC (<em>(N)</em>-1-(2-nitrophenyl)ethyl) caged version of serotonin.
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| BCC7837 | NPEC-caged-dopamine |
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NPEC (<em>(N)</em>-1-(2-nitrophenyl)ethyl) caged version of dopamine; releases dopamine leading to D<sub>1</sub> receptor activation upon UV light illumination (360 nm). Induces PKA activation and c-Fos expression in cortical and striatal neurons, with striatal neurons demonstrating a significantly greater detection and sensitivity to sub-second dopamine signals as compared to cortical neurons.
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| BCC7838 | Zotepine |
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5-HT2A receptor and dopamine D2 receptor antagonist (Ki values are 0.69 and 2.3 nM respectively). Also a potent histamine H1 receptor antagonist (IC50 = 8.0 nM). Atypical antipsychotic; exhibits antidepressive and anxiolytic effects in vivo.
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| BCC7839 | Cyclofenil |
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Non-steroidal selective estrogen receptor modulator (SERM). Displays higher affinity for estrogen receptor <span class='symbol'>β</span> (ER<span class='symbol'>β</span>) than for ER<span class='symbol'>α</span>.
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| BCC7840 | L 760735 |
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High affinity NK<sub>1</sub> receptor antagonist (IC<sub>50</sub> = 0.19 nM at human NK<sub>1</sub> receptors). Selective (>300-fold) over h-NK<sub>2</sub> and h-NK<sub>3</sub> receptors. Exhibits anxiolytic and antidepressant-like effects. Orally active.
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| BCC7841 | IDE 1 |
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Induces definitive endoderm formation in mouse and human embryonic stem cells (ESCs) (EC<sub>50</sub> = 125 nM). Thought to activate the TGF-<span class='symbol'>β</span> signaling pathway; induces Smad2 phosphorylation and increases levels of Nodal expression.
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| BCC7842 | JNJ 10181457 dihydrochloride |
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Histamine H3 receptor antagonist (pKi values are 8.15 and 8.93 for rat and human H3 receptors respectively). Increases extracellular norepinephrine and acetylcholine levels in rat frontal cortex but does not stimulate dopamine release. Brain penetrant.
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| BCC7843 | 16,16-Dimethyl Prostaglandin E2 |
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Synthetic derivative of prostaglandin E<sub>2</sub>. Increases embryonic stem cell (ESC) hematopoietic colony formation in mouse bone marrow. Also induces an increase in hematopoietic stem cell (HSC) numbers and enhances Wnt activity within the HSC population in zebrafish embryos.
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