Hot Natural Products & Bioactive Compounds

BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.

Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.

Hot Products from BioCrick

Showing 3257 - 3264 of 9359 hot products

BioCrick hot natural products and bioactive compounds
Catalog No. Product Name
BCC7828 Tesaglitazar
Dual-specificity PPAR<span class='symbol'>&#945;</span>/<span class='symbol'>&#947;</span> agonist (IC<sub>50</sub> values are 0.35 and 3.8 <span class='symbol'>&#956;</span>M for PPAR<span class='symbol'>&#947;</span> and PPAR<span class='symbol'>&#945;</span> respectively). Prevents atherosclerosis progression in E3L.CETP transgenic mice. Also reduces insulin resistance in obese Zucker rats. Orally active.
BCC7829 AA 29504
Positive allosteric modulator of GABA<sub>A</sub> receptors. Modulates both <span class='symbol'>&#945;</span><sub>4</sub><span class='symbol'>&#946;</span><sub>3</sub><span class='symbol'>&#948;</span>-containing extrasynaptic receptors and <span class='symbol'>&#945;</span><sub>1</sub><span class='symbol'>&#946;</span><sub>3</sub><span class='symbol'>&#947;</span><sub>2S</sub>-containing receptors in <em>Xenopus</em> oocytes, displaying a stronger modulatory effect at the former. Reduces motor coordination and exhibits anxiolytic effects <em>in vivo</em>.
BCC7830 Latrunculin A
Reversible inhibitor of actin assembly; blocks actin adenine nucleotide exchange. Complexes with actin in vitro and interacts with actin monomers only, unlike cytochalasins. Prevents actin repolymerization into filaments and disrupts the actin cytoskeleton.
BCC7831 Zearalenone
Mycotoxin produced by several species of <em>Fusarium</em> fungi. Binds to the estrogen receptor (ER) (IC<sub>50</sub> values are 166 and 240 nM for ER<span class='symbol'>&#946;</span> and ER<span class='symbol'>&#945;</span> respectively) and stimulates the transcriptional activity of both subtypes at concentrations between 1 - 10 nM. Also stimulates growth of T47D breast cancer cells.
BCC7832 Deoxynivalenol
Tricothecene mycotoxin and potent protein synthesis inhibitor. Exhibits cytotoxic activity <em>in vivo</em> via the ribotoxic stress response. Induces p38-mediated gene expression and apoptosis in leukocytes; activity results in systemic expression of interleukin-6 (IL-6) and other proinflammatory cytokines. Also induces migration of NF-<span class='symbol'>&#954;</span>B into the nucleus.
BCC7833 SR 58611A hydrochloride
Selective <span class='symbol'>&#946;</span>3-adrenergic receptor agonist. Displays both anxiolytic and antidepressant effects in rodent models. Orally active and brain penetrant.
BCC7834 AMTB hydrochloride
TRPM8 channel blocker. Inhibits icilin</a>-induced TRPM8 channel activation in a rat model (pIC<sub>50</sub> = 6.23).
BCC7835 NPEC-caged-noradrenalin
Noradrenalin caged with the photosensitive 1-(2-nitrophenyl)ethoxycarbonyl (NPEC) group.