Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN5162 | Xanthohumol D |
| 1. Xanthohumol and xanthohumol D are potent inducers of quinone reductase, suggests that they could be used as chemoprevention agents. | |
| BCN5164 | Feretoside |
| Feretoside can increase the expression of heat shock factor 1 (HSF1) by a factor of 1.153 at 3 uM. | |
| BCN5165 | Baccatin III |
| Baccatin III, which is the precursor for the semisynthesis of paclitaxel,exerts anti-tumor immunomodulatory activity in very low doses (0.05-0.5mg/kg),it reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs. Baccatin III also exerts immunomodulatory activities in vivo as well as in vitro on the MHC-restricted antigen presentation. | |
| BCN5166 | Communic acid |
| 1. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmetic ingredients, as they suppress UVB-induced MMP-1 expression. 2. Communic acid has antibacterial activity, including against mycobacterial. 3. trans-Communic acid exhibits protective effects against UVB-induced skin aging by suppressing UVB-induced MMP-1 expression. 4. trans-Communic acid shows considerable cytotoxicity against four human cancer cell lines in vitro. 5. trans-Communic acid shows good activity against Mycobacterium aurum (MIC of 13.2 microM). | |
| BCN5167 | Leucoside |
| Pure leucoside can be prepared by enzymatic partial hydrolysis of tea seed extract . | |
| BCN5170 | Erysotrine |
| 1. Erysotrine does not show cytotoxic activity by itself, but exhibits significant cytotoxicity when combines with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). 2. (+)-Erysotrine shows potent dosedependant antifeedant activity at concentrations ≥100 ppm. | |
| BCN5171 | Geniposidic acid |
| Geniposidic acid is an effective anticancer and radioprotection agent, used to treat inflammation, jaundice and hepatic disorders. It has anti-atherosclerotic effects, can protect vascular endothelium and reverse plaque formation in an atherosclerotic model. Geniposidic acid has effects on the expression of MRP2 and BSEP in BRL-3A cells after FXR gene silencing mediated by si RNA. | |
| BCN5172 | Ervamycine |
| 1. 11-Methoxytabersonine(Ervamycine) exhibits inhibitory effects against five human cancer cell lines , with IC(50) values comparable to those of cisplatin and vinorelbine. | |
