Hot Natural Products & Bioactive Compounds

BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.

Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.

Hot Products from BioCrick

Showing 3209 - 3216 of 9359 hot products

BioCrick hot natural products and bioactive compounds
Catalog No. Product Name
BCC7779 NS 1619
Large-conductance Ca<sup>2+</sup>-activated potassium (BK<sub>Ca</sub>, K<sub>Ca</sub>1.1) channel activator. Induces a concentration-dependent decrease in mitochondrial membrane potential (EC<sub>50</sub> = 3.6 <span class='symbol'>&#956;</span>M).
BCC7780 Cl-4AS-1
Potent steroidal androgen receptor agonist (IC<sub>50</sub> = 12 nM). Mimics the action of 5<span class='symbol'>&#945;</span>-dihydrotestosterone (DHT). Transactivates the mouse mammary tumor virus (MMTV) promoter; represses MMP1 promoter activity. Inhibits 5<span class='symbol'>&#945;</span>-reductase type I and II (IC<sub>50</sub> values are 6 and 10 nM respectively).
BCC7781 R 568 hydrochloride
Positive allosteric modulator and allosteric agonist of the human calcium-sensing receptor (hCaSR). Exhibits calcimimetic activity. Has the ability to restore function to hCaSR mutants that cause familial hypocalciuric hypercalcemia (FHH) and neonatal severe hyperparathyroidism (NSHPT). Exerts a suppressive effect on parathyroid (PT) hormone secretion; inhibits PT cell proliferation in rats with renal insufficiency.
BCC7782 MM 11253
Selective RAR<span class='symbol'>&#947;</span> antagonist. Blocks the growth inhibitory ability of RAR<span class='symbol'>&#947;</span>-selective agonists in squamous cell carcinoma (SCC)-25 cells.
BCC7783 ER 50891
Antagonist of RAR<span class='symbol'>&#945;</span> receptors (IC<sub>50</sub> = 31.2 nM). Displays selective affinity for RAR<span class='symbol'>&#945;</span> (relative IC<sub>50</sub> values are 1.8, 432 and 535 nM for RAR<span class='symbol'>&#945;</span>, RAR<span class='symbol'>&#947;</span> and RAR<span class='symbol'>&#946;</span> respectively).
BCC7784 UK 78282 hydrochloride
Blocker of the K<sub>V</sub>1.3 and K<sub>V</sub>1.4 voltage-gated potassium channels in T lymphocytes (IC<sub>50</sub> values are 0.28 and 0.17 <span class='symbol'>&#956;</span>M respectively). Suppresses T lymphocyte mitogenesis; leads to membrane depolarization. Also blocks K<sub>V</sub>1.4 expressed in heart and brain.
BCC7785 NF 340
P2Y<sub>11</sub> antagonist; exhibits 520-fold selectivity for P2Y<sub>11</sub> over P2Y<sub>1</sub>, P2Y<sub>2</sub>, P2Y<sub>4</sub>, P2Y<sub>6</sub> and P2Y<sub>12</sub> receptors. Displays competitive antagonism against ATP<span class='symbol'>&#947;</span>S (pIC<sub>50</sub> values are 6.43 and 7.14 in Ca<sup>2+</sup> and cAMP assays respectively).
BCC7786 LG 100754
Novel RXR:PPAR<span class='symbol'>&#947;</span> agonist; sensitizes PPAR<span class='symbol'>&#947;</span> by enhancing its ligand binding activity. Also activates RXR:RAR and RXR:PPAR<span class='symbol'>&#945;</span> heterodimers in cotransfection assays. Displays selectivity over other permissive heterodimers such as RXR:LXR<span class='symbol'>&#945;</span> and RXR:BAR/FXR. Exhibits antidiabetic properties <em>in vivo</em>.