Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN5068 | Epifriedelanol acetate |
| 1. Epifriedelanol exhibits antibacterial activities. 2. Epifriedelanol and friedelin possess promising antioxidant activity, and they are active against the two cancer cells (human T4 lymphoblastoid (CEM-SS) and human cervical (HeLa) cancer cells) with IC50 values ranging from 3.54 to11.45 ug/ml. 3. Epifriedelanol can reduce cellular senescence in human primary cells and may be used to develop dietary supplements or cosmetics that modulate tissue aging or aging-associated diseases. | |
| BCN5069 | Torachrysone |
| 1. Torachrysone, toralactone , aloe-emodin, rhein and emodin show noticeable antibacterial effects on four strains of methicillin-resistant Staphylococcus aureus with a minimum inhibitory concentration of 2-64 micrograms/ml. 2. Torachrysone shows promising antioxidant activity. | |
| BCN5072 | Mucrolidin |
| 1. Mucrolidin shows weak antibacterial activity. | |
| BCN5074 | Ecdysterone 2,3:20,22-diacetonide |
| 1. Due to the multi-drug resistance reversal activity of the less polar ecdysteroids, several new products( including 20-hydroxyecdysone,20-hydroxyecdysone 2,3;20,22-diacetonide) are promising for being tested against various cancer cell lines. | |
| BCN5076 | 6-Acetonyldihydrochelerythrine |
| 1. 6-Acetonyldihydrochelerythrine exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therapeutic Index) values of 1.77 microg/mL and 14.6, respectively. 2. 6-Acetonyldihydrochelerythrine is a potent inducer of apoptosis in HCT116 and SW620 cell lines, it displays potent cytotoxic activity in human HCT116 and SW620 colon carcinoma cells, to a higher extent than 5-fluorouracil (5-FU), the cornerstone chemotherapeutic agent in colon cancer. 3. 6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities. | |
| BCN5079 | Heveaflavone |
| 1. Heveaflavone has anti-proliferation effects. 2. Heveaflavone shows moderate Topoisomerase I inhibitory activity. 3. Heveaflavone possesses a good antioxidant activity via its DPPH free radical scavenging. | |
| BCN5080 | Strictosamide |
| 1. Strictosamide may have important effects on inflammation and inflammatory pain. 2. Strictosamide is slightly toxic to Charles River mouse (LD(50)=723.17 mg/kg), producing CNS depression and kidney toxicity. 3. Strictosamide has nonsignificant in vitro and in vivo effect on kidney Na(+),K(+)-ATPase activity but produced an in vivo increase of Na(+),K(+)-ATPase activity of brain. 4. Strictosamide possesses antibacterial and antiviral activities. | |
| BCN5081 | Vincosamide |
| 1. Vincosamide can effect relaxation of the supercoiled pBR322 plasmid DNA in the presence of Cu2+. | |
