Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 3169 - 3176 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7737 | Allopregnanolone |
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Neuroactive steroid, an endogenous modulator of GABAA mediated chloride ion conductance.
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| BCC7738 | Neurodazine |
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Induces neurogenesis of non-pluripotent C2C12 myoblasts and cells derived from mature human skeletal muscle. Upregulates the expression of neuron-specific markers in C2C12 cells.
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| BCC7739 | GYY 4137 morpholine salt |
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Slow-releasing H2S donor. Exhibits vasodilator and antihypertensive activity. Activity causes slow dilation of blood vessels in vitro and in vivo; does not influence vascular smooth muscle cell viability in culture. Water-soluble.
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| BCC7740 | BMS 195614 |
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Neutral retinoic acid receptor (RAR) <span class='symbol'>α</span>-selective antagonist (K<sub>i</sub> = 2.5 nM). Displays no significant effect on nuclear receptor corepressor (NCoR) binding; moderately decreases SMRT binding to RAR. Antagonizes agonist-induced coactivator (CoA) recruitment.
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| BCC7741 | GSK 4112 |
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Selective Rev-Erb<span class='symbol'>α</span> agonist (EC<sub>50</sub> = 250 nM). Enhances recruitment of nuclear receptor co-repressor (NCoR) peptide to Rev-Erb<span class='symbol'>α</span>; causes acute suppression of <em>Bmal1</em> gene transcription. Induces phase shifts in the circadian clock.
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| BCC7742 | Donitriptan hydrochloride |
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Brain penetrant 5-HT1B/1D agonist (pKi values are 9.3 and 9.4 for 5-HT1D and 5-HT1B respectively). Inhibits capsaicin-induced external carotid vasodilation and produces selective carotid vasoconstriction in various animal species. Displays antimigraine activity.
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| BCC7743 | SKA 31 |
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Activator of KCa3.1 and KCa2 channels (EC50 values are 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively). Potentiates acetylcholine-induced EDHF-type dilations of mouse carotid arteries and lowers blood pressure in normotensive and hypertensive mice.
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| BCC7744 | RF 9 |
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Selective NPFF receptor antagonist (Ki values are 58 and 75 nM at hNPFF1 and hNPFF2 receptors respectively). Displays selectivity over several related receptors including NPY Y1 GPR10, GPR54, GPR103 and the opioid receptors. Blocks NPFF-induced hypothermia and increases in atrial blood pressure and heart rate, and prevents opioid-induced tolerance associated with hyperalgesia in vivo.
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