Docosyl caffeate

CAS# 28593-92-2

Docosyl caffeate

Catalog No. BCN5182----Order now to get a substantial discount!

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Docosyl caffeate: 5mg $477 In Stock
Docosyl caffeate: 10mg Please Inquire In Stock
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Docosyl caffeate: 500mg Please Inquire Please Inquire
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Quality Control of Docosyl caffeate

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Chemical structure

Docosyl caffeate

3D structure

Chemical Properties of Docosyl caffeate

Cas No. 28593-92-2 SDF Download SDF
PubChem ID 5316952 Appearance Powder
Formula C31H52O4 M.Wt 488.8
Type of Compound Phenylpropanoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name docosyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
SMILES CCCCCCCCCCCCCCCCCCCCCCOC(=O)C=CC1=CC(=C(C=C1)O)O
Standard InChIKey GUWHMEMJBCLEBP-WJTDDFOZSA-N
Standard InChI InChI=1S/C31H52O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-26-35-31(34)25-23-28-22-24-29(32)30(33)27-28/h22-25,27,32-33H,2-21,26H2,1H3/b25-23+
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Docosyl caffeate

The roots of Glycyrrhiza uralensis Fisch

Biological Activity of Docosyl caffeate

Description1. Docosyl caffeate exhibits potent elastase inhibitory activity, with the IC50 value of 1.4 microg/mL . 2. Docosyl caffeate shows moderate antioxidant activity in DPPH and ABTS scavenging assays. 3. Docosyl caffeate has significant anti-inflammation activity in mice with ear swelling.
TargetsImmunology & Inflammation related

Docosyl caffeate Dilution Calculator

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Docosyl caffeate Molarity Calculator

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Preparing Stock Solutions of Docosyl caffeate

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0458 mL 10.2291 mL 20.4583 mL 40.9165 mL 51.1457 mL
5 mM 0.4092 mL 2.0458 mL 4.0917 mL 8.1833 mL 10.2291 mL
10 mM 0.2046 mL 1.0229 mL 2.0458 mL 4.0917 mL 5.1146 mL
50 mM 0.0409 mL 0.2046 mL 0.4092 mL 0.8183 mL 1.0229 mL
100 mM 0.0205 mL 0.1023 mL 0.2046 mL 0.4092 mL 0.5115 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Docosyl caffeate

Bioactive caffeic acid esters from Glycyrrhiza glabra.[Pubmed:19921583]

Nat Prod Res. 2009;23(18):1657-63.

Thin layer chromatography bioautography (using DPPH spray reagent) guided fractionation of Glycyrrhiza glabra led to the isolation of two caffeic acid derivative esters, viz. eicosanyl caffeate (1) and Docosyl caffeate (2). The two compounds exhibited potent elastase inhibitory activity, with IC(50) values of 0.99 microg mL(-1) and 1.4 microg mL(-1) for 1 and 2, respectively. The compounds also showed moderate antioxidant activity in DPPH and ABTS scavenging assays. The results indicate a possible role of caffeic acid derivatives, in addition to flavonoids in the anti-ulcer properties of G. glabra.

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