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Erythristemine

CAS# 28619-41-2

Erythristemine

2D Structure

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Quality Control of Erythristemine

3D structure

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Erythristemine

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Chemical Properties of Erythristemine

Cas No. 28619-41-2 SDF Download SDF
PubChem ID 12143915 Appearance Powder
Formula C20H25NO4 M.Wt 343.4
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R,9R,13bS)-2,9,11,12-tetramethoxy-2,6,8,9-tetrahydro-1H-indolo[7a,1-a]isoquinoline
SMILES COC1CC23C(=CCN2CC(C4=CC(=C(C=C34)OC)OC)OC)C=C1
Standard InChIKey IUMRZRWBQPPMSS-GKCIPKSASA-N
Standard InChI InChI=1S/C20H25NO4/c1-22-14-6-5-13-7-8-21-12-19(25-4)15-9-17(23-2)18(24-3)10-16(15)20(13,21)11-14/h5-7,9-10,14,19H,8,11-12H2,1-4H3/t14-,19-,20-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Erythristemine

The barks of Aralia chinensis

Biological Activity of Erythristemine

Description1. (+)-Erythristemine shows moderate toxicity to brine shrimp (LC50 23 ppm) and moderate (IC50=86microg/ml) radical scavenging properties against stable 2,2-diphenyl-1-picrylhy--drazyl (DPPH) radical.

Erythristemine Dilution Calculator

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Erythristemine Molarity Calculator

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Preparing Stock Solutions of Erythristemine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9121 mL 14.5603 mL 29.1206 mL 58.2411 mL 72.8014 mL
5 mM 0.5824 mL 2.9121 mL 5.8241 mL 11.6482 mL 14.5603 mL
10 mM 0.2912 mL 1.456 mL 2.9121 mL 5.8241 mL 7.2801 mL
50 mM 0.0582 mL 0.2912 mL 0.5824 mL 1.1648 mL 1.456 mL
100 mM 0.0291 mL 0.1456 mL 0.2912 mL 0.5824 mL 0.728 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Erythristemine

Erythrinaline alkaloids from the flowers and pods of Erythrina lysistemon and their DPPH radical scavenging properties.[Pubmed:15231413]

Phytochemistry. 2004 May;65(10):1397-404.

Fourteen different erythrinaline alkaloids have been isolated from the flowers and pods of Erythrina lysistemon with four being reported for the first time in nature and five for the first time in this species and the rest having been re-isolated. The new compounds are (+)-11beta-hydroxyerysotramidine (1), (+)-11beta-methoxyerysotramidine (2), (+)-11beta-hydroxyerysotrine N-oxide (4) and (+)-11beta-hydroxyerysotrine (8). (+)-11alpha-Hydroxyerysotrine N-oxide (3), earlier misidentified as erythrartine N-oxide (beta-hydroxyerysotrine N-oxide 4), was also re-isolated along with four other alkaloids. Correct identification of compounds 4 and 8 was aided by the fact that the two sets of C-11 epimers 3, 4 and 8, 9 were both isolated in this study thus making it easier to identify and assign the individual epimers. (+)-Erythristemine (14) was found distributed in most of the plant parts investigated. Preliminary work on the crude chloroform/methanol (1:1) showed moderate toxicity to brine shrimp (LC50 23 ppm) and moderate (IC50 86 microg/ml) radical scavenging properties against stable 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. The DPPH radical scavenging properties of the isolated compounds were assessed using TLC autographic and spectrophotometric assays whereupon only compounds 11 (1 microg; 90 microg/ml) and 12 (0.1 microg; 160 microg/ml) showed any notable activity. It appears the two compounds are slow reacting and do not reach steady state conditions within the standard half an hour time frame but only seemed to have reached steady state conditions after 4 h.

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