Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 3081 - 3088 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7649 | VU 1545 |
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Metabotropic glutamate receptor 5 (mGlu<sub>5</sub>) positive allosteric modulator (EC<sub>50</sub> = 9.6 nM, K<sub>i</sub> = 156 nM at rat mGlu<sub>5</sub>).
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| BCC7650 | BGC 20-761 |
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Selective, high affinity 5-HT<sub>6</sub> antagonist (K<sub>i</sub> = 20 nM). Reverses the amnesic effects of scopolamine and enhances memory consolidation in a rat model.
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| BCC7651 | Desformylflustrabromine hydrochloride |
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Positive allosteric modulator of nicotinic <span class='symbol'>α</span>4<span class='symbol'>β</span>2 receptors; selectively increases the ionic current through <span class='symbol'>α</span>4<span class='symbol'>β</span>2 in the presence of ACh. Displays 14.7-fold selectivity for <span class='symbol'>α</span>4<span class='symbol'>β</span>2 over homomeric (<span class='symbol'>α</span>7) receptors. Moderately cytotoxic in HCT-116 cells. Also inhibits human muscle (<span class='symbol'>α</span><span class='symbol'>β</span><span class='symbol'>ε</span><span class='symbol'>δ</span>) and <em>Torpedo</em> (<span class='symbol'>α</span><span class='symbol'>β</span><span class='symbol'>γ</span><span class='symbol'>δ</span>) nAChRs (IC<sub>50</sub> values are 1.0 and 0.1 <span class='symbol'>μ</span>M, respectively) by binding in the ion channel.
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| BCC7652 | NPEC-caged-(S)-3,4-DCPG |
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(<em>S</em>)-3,4-DCPG caged with the photosensitive 1-(2-nitrophenyl)ethoxycarbonyl group.
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| BCC7653 | NPEC-caged-(1S,3R)-ACPD |
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(1<em>S</em>,3<em>R</em>)-ACPD caged with the photosensitive 1-(2-nitrophenyl)ethoxycarbonyl (NPEC) group.
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| BCC7654 | L-798,106 |
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Potent and highly selective prostanoid EP<sub>3</sub> receptor antagonist (K<sub>i</sub> values are 0.3, 916, > 5000 and > 5000 nM at EP<sub>3</sub>, EP<sub>4</sub>, EP<sub>1</sub> and EP<sub>2</sub> respectively). Attenuates sulprostone-induced inhibition of EFS-evoked twitch and contractile responses <em>in vivo</em>.
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| BCC7655 | Ro 8-4304 hydrochloride |
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NMDA receptor antagonist (IC<sub>50</sub> = 0.4 <span class='symbol'>μ</span>M) that displays > 100 fold selectivity for NR2B-containing receptors over NR2A-containing receptors. Exhibits an activity-dependent mechanism of NMDA antagonism and is competitive with respect to spermine .
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| BCC7656 | SLV 320 |
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Potent and selective adenosine A<sub>1</sub> receptor antagonist (K<sub>i</sub> values are 1, 200, 398 and 3981 nM at human A<sub>1</sub>, A<sub>3</sub>, A<sub>2A</sub> and A<sub>2B</sub> receptors respectively). Suppresses cardiac fibrosis and attenuates albuminuria, without effect on blood pressure in animal models of chronic renal failure. Orally active.
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