Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 3033 - 3040 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7601 | Kifunensine |
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Inhibitor of class I <span class='symbol'>α</span>-mannosidases that inhibits glycoprotein processing. Inhibits human endoplasmic reticulum <span class='symbol'>α</span>-1,2-mannosidase I and Golgi Class I mannosidases IA, IB and IC with K<sub>i</sub> values of 130 and 23 nM respectively.
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| BCC7602 | Swainsonine |
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Inhibitor of <span class='symbol'>α</span>-mannosidase II which inhibits glycoprotein processing. Displays anticancer and immune modulatory properties.
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| BCC7603 | alpha,beta-Methyleneadenosine 5'-triphosphate trisodium salt |
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P2-purinoceptor agonist. Also shown to inhibit adenylate cyclase (Ki = 0.5 mM).
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| BCC7604 | CP 376395 hydrochloride |
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Potent and selective CRF<sub>1</sub> receptor antagonist (K<sub>i</sub> values are 12 and >10000 nM for CRF<sub>1</sub> and CRF<sub>2</sub> receptors respectively). Attenuates CRF-induced activation of the HPA axis <em>in vivo</em> following i.v. administration. Orally active.
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| BCC7605 | CGP 36216 hydrochloride |
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Selective GABA<sub>B</sub> antagonist. Displays activity at presynaptic receptors; ineffective at GABA<sub>B</sub> postsynaptic receptors.
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| BCC7606 | bPiDDB |
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Orthosteric neuronal nicotinic acetylcholine receptor (nAChR) antagonist (IC<sub>50</sub> values are 0.17, 0.25, 0.4, 4.8, 6.5, 8.2, 20 and 34 <span class='symbol'>μ</span>M at <span class='symbol'>α</span>3<span class='symbol'>β</span>4, <span class='symbol'>α</span>1<span class='symbol'>β</span>1<span class='symbol'>ε</span><span class='symbol'>δ</span>, <span class='symbol'>α</span>3<span class='symbol'>β</span>4<span class='symbol'>β</span>3, <span class='symbol'>α</span>6<span class='symbol'>β</span>4<span class='symbol'>β</span>3, <span class='symbol'>α</span>7, <span class='symbol'>α</span>4<span class='symbol'>β</span>2, <span class='symbol'>α</span>3<span class='symbol'>β</span>2<span class='symbol'>β</span>3 and <span class='symbol'>α</span>6/3<span class='symbol'>β</span>2<span class='symbol'>β</span>3 receptors respectively). Attenuates nicotine-evoked dopamine release from the ventral tegmental area <em>in vivo</em> (IC<sub>50</sub> = 0.2 nM) and reduces nicotine self-administration in rats. Brain penetrant.
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| BCC7607 | TCS JNK 6o |
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ATP-competitive c-Jun N-terminal kinase (JNK) inhibitor (IC<sub>50</sub> values are 2, 4 and 52 nM for JNK1, JNK2 and JNK3 respectively). Displays > 1000 fold selectivity over other kinases, including ERK2 and p38. Inhibits c-Jun phosphorylation (EC<sub>50</sub> = 920 nM) and prevents collagen-induced platelet aggregation <em>in vitro</em>.
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| BCC7608 | RU 58668 |
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Pure antiestrogen that downregulates estrogen receptor expression (IC<sub>50</sub> = 0.04 nM). Displays potent antiproliferative activity <em>in vitro</em> (IC<sub>50</sub> = 0.035 - 0.09 nM in MCF-7 cells) and causes long term regression of tamoxifen-resistant MCF-7 xenografts <em>in vivo</em>.
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