Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN4828 | Erythrabyssin II |
| 1. Erythrabyssin II actives against several strains of Staphylococcus and Streptococcus with an MIC range of 0.78-1.56 microg/ml. 2. Erythrabyssin II inhibits bacterial neuraminidase in a dose-dependent manner with significant inhibition (IC(50)=0.09-3.25 μM). | |
| BCN4831 | Citropten |
| Citropten and valproic acid show antiproliferative effects against A2058 human melanoma cells. | |
| BCN4842 | Pterisolic acid A |
| 1. Pterisolic acid A shows moderate activity against HCT-116,Hep G2 and BGC-823 cell lines. | |
| BCN4843 | Pterisolic acid B |
| 1. Pterisolic acid B (J19) is an effective Nrf2 activator. we have also identified a more potent natural product analogue J19-1, J19-1 shows significant cytoprotective effect against cisplatin-induced cytotoxicity in HKC cells. | |
| BCN4846 | Sanggenon N |
| 1. Sanggenon N shows protective effects on t-BHP-induced oxidative stress with the EC50 value of 23.45 ± 4.72 uM. 2. Sanggenon N inhibits lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages. | |
| BCN4853 | Enniatin B1 |
| 1. Enniatin B1 has intestinal toxicity. 2. Enniatins A, A(1), B, B(1) have antifungal effects. 3. Enniatins A1, B and B1 induce apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation. | |
| BCN4857 | Atalantoflavone |
| 1. Atalantoflavone shows urease inhibitory potential. 2. Atalantoflavone displays weak cytotoxic activity against the human Caucasian prostate adenocarcinoma cell line PC-3. | |
| BCN4861 | 11-Hydroxytephrosin |
| 1. 11-Hydroxytephrosin inhibits NF-kappaB activity. | |
