Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2969 - 2976 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7535 | NS 1738 |
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Selective positive allosteric modulator of <span class='symbol'>α</span>7 nicotinic acetylcholine receptors. Exhibits no substantial activity for <span class='symbol'>α</span>4<span class='symbol'>β</span>2, <span class='symbol'>α</span>3<span class='symbol'>β</span>3 and <span class='symbol'>α</span>1-containing receptors. Displays cognitive-enhancing properties <em>in vivo</em>.
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| BCC7536 | 1-Methylpsilocin |
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Potent and selective 5-HT2C agonist (IC50 values are 12 and 633 nM for 5-HT2C and 5-HT2A receptors respectively). Displays high affinity for the 5-HT2B receptor (Ki = 38 nM) but acts as an inverse agonist. Active in vivo; inhibits scratching in a mouse model of OCD.
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| BCC7537 | Edelfosine |
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Synthetic lysophospholipid analog that selectively inhibits phosphatidylinositol phospholipase C (IC<sub>50</sub>= 9.6 <span class='symbol'>μ</span>M in fibroblasts and adenocarcinoma cells). Also acts as an agonist at platelet-activating factor (PAF) receptors. Antitumor lipid; selectively induces apoptosis in tumor cells, sparing normal cells.
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| BCC7538 | Rp-8-Br-PET-cGMPS |
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Competitive, reversible cGMP-dependent protein kinase (PKG) inhibitor; cGMP analog.
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| BCC7539 | THIQ |
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Potent and selective melanocortin 4 (MC4) receptor agonist (IC50 values are 1.2, 761 and 2067 nM for human MC4, MC3 and MC1 receptors respectively). Enhances intracavernosal pressure and stimulates erectile activity in rats ex copula following systemic administration.
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| BCC7540 | NSC 109555 ditosylate |
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Selective, reversible, ATP-competitive Chk2 inhibitor (IC<sub>50</sub> = 0.2 <span class='symbol'>μ</span>M) that displays no effect on a range of other kinases including Chk1 (IC<sub>50</sub> > 10 <span class='symbol'>μ</span>M). Inhibits histone H1 phosphorylation (IC<sub>50</sub> = 0.24 <span class='symbol'>μ</span>M) and attenuates mitochondrial ATP synthesis. Exhibits antiproliferative activity in a number of leukemias <em>in vivo</em>.
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| BCC7541 | TCS 2312 |
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Potent and selective checkpoint kinase 1 (chk1) inhibitor (K<sub>i</sub> = 0.38 nM, EC<sub>50</sub> = 60 nM). Enhances the cell killing activity of Gemcitabine in breast and prostate cancer cell lines and displays antiproliferative effects <em>in vitro</em>.
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| BCC7542 | YM 750 |
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Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC<sub>50</sub> = 0.18 <span class='symbol'>μ</span>M). Exhibits hypocholesterolaemic and antiatherosclerotic activity <em>in vivo</em>.
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