Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN4773 Phyllostine
1. Phyllostine appears to be their more immediate precursor, since PCMB-treated extracts of J2 converted Phyllostine but not isoepoxydon to these new metabolites.
BCN4774 Enniatin B
1. Enniatin B can decrease Monocytes' endocytosis ability and an increase of CD71. 2. Enniatin B has anticancer benefits, especially for the treatment of cervical cancer. 3. Enniatin B has extensive hepatic metabolism, that reduces in vivo potential . 4. Enniatin B has antiangiogenic properties, indicated by a strong inhibition of human endothelial cell migration and tube formation.
BCN4775 3',4'-Dihydroxyacetophenone
1. 3',4'-Dihydroxyacetophenone has antimicrobial activity.
BCN4780 Persicoside
1. Persicoside exhibits radical scavenging activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical.
BCN4782 Alstoyunine E
1. Alstoyunine E shows selective inhibition of Cox-2 (>75%).
BCN4786 Altholactone
1. Altholactone can inhibit the growth of various types of cancer cells through inducing apoptosis via oxidative stress, including bladder cancer, colon carcinoma cells. 2. Altholactone may be a potential antimicrobial agent, particularly in ciprofloxacin-refractory S. aureus and E. faecalis infections.
BCN4788 Warangalone
1. Warangalone shows significant cytotoxicity against HL-60 cells. 2. Warangalone with cAK may contribute to its biological effects in vivo and to the insecticidal activity of the plant D. scandens. 3. Warangalone is a powerful inhibitor of protein kinase A, shows marked effectiveness as an anti-inflammatory on the phospholipase A(2)-induced paw edema and on the 12-O-tetradecanoylphorbol 13-acetate-induced ear edema in mice, after systemic and local administration, respectively.
BCN4789 Osajin
1. Osajin shows antitumor activity in different tumor cell lines. 2. The cardioprotection provided by Osajin treatment results from the suppression of oxidative stress and correlates with the improved ventricular function. 3. Osajin induces apoptosis in human NPC cells through multiple apoptotic pathways, including the extrinsic death receptor pathway, and intrinsic pathways relying on mitochondria and endoplasmic reticulum stress.