Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2985 - 2992 of 9359 hot products
| Catalog No. | Product Name |
|---|---|
| BCC7551 | Macbecin I |
|
Ansamycin antibiotic compound that inhibits Hsp90 activity (IC<sub>50</sub> = 2 <span class='symbol'>μ</span>M) by binding to the ATP-binding site. Exhibits antitumor and cytocidal activities (IC<sub>50</sub> ~ 0.4 <span class='symbol'>μ</span>M) by causing degradation of key oncogenic client proteins such as ErbB2 and cRaf1. Displays higher affinity and potency than geldanamycin.
|
|
| BCC7552 | NS 1643 |
|
Human ether-a-go-go related gene (hERG) K<sub>V</sub>11.1 channel activator (EC<sub>50</sub> = 10.5 <span class='symbol'>μ</span>M). Exhibits different molecular mechanisms of action at K<sub>V</sub>11.1 (hERG1) and K<sub>V</sub>11.2 (hERG2) channels. Displays antiarrhythmic activity <em>in vitro</em>.
|
|
| BCC7553 | Desipramine hydrochloride |
|
Tricyclic antidepressant that is a selective inhibitor of noradrenalin transporters (K<sub>i</sub> values are 4, 61 and 78720 nM for NET, SERT and DAT transporters respectively).
|
|
| BCC7554 | Tetraethylammonium chloride |
|
Non-selective K<sup>+</sup> channel blocker.
|
|
| BCC7555 | Acephate |
|
Anticholinesterase insecticide that produces cholinotoxicity. Displays weak inhibition of rat acetylcholinesterase (AChE) but potently inhibits cockroach AChE.
|
|
| BCC7556 | (+)-Muscarine iodide |
|
Muscarinic acetylcholine receptor agonist; mimics the activity of acetylcholine.
|
|
| BCC7557 | GSK 4716 |
|
Selective agonist at estrogen-related receptors ERR<span class='symbol'>β</span> and ERR<span class='symbol'>γ</span>. Displays selectivity over ERR<span class='symbol'>α</span> and the classical estrogen receptors.
|
|
| BCC7558 | LY 272015 hydrochloride |
|
High affinity 5-HT<sub>2B</sub> receptor antagonist that displays selectivity over 5-HT<sub>2A</sub> and 5-HT<sub>2C</sub> receptors (K<sub>i</sub> values are 0.75, 21.63 and 28.7 nM for 5-HT<sub>2B</sub>, 5-HT<sub>2C</sub> and 5-HT<sub>2A</sub> receptors respectively). Orally active.
|
|