Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2953 - 2960 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7518 | FPA 124 |
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Akt/PKB inhibitor (IC<sub>50</sub> = 100 nM) that interacts with the PH and kinase domains. Inhibits cell proliferation in various cancer cell lines <em>in vitro</em> and decreases NF-<span class='symbol'>κ</span>B activity and tumor load <em>in vivo</em>.
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| BCC7520 | CP 465022 hydrochloride |
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Selective, non-competitive AMPA antagonist (IC50 = 25 nM in rat cortical neurons) that displays potent anticonvulsant activity. Also significantly blocks the persistent component of Nav1.6 channel activity. Brain penetrant and orally active.
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| BCC7521 | Atipamezole hydrochloride |
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Selective <span class='symbol'>α</span><sub>2</sub>-adrenergic receptor antagonist (K<sub>i</sub> values are 1.1, 1.0, 0.89, 1300 and 6500 nM for <span class='symbol'>α</span><sub>2A</sub>, <span class='symbol'>α</span><sub>2B</sub>, <span class='symbol'>α</span><sub>2C</sub>, <span class='symbol'>α</span><sub>1A</sub> and <span class='symbol'>α</span><sub>1B</sub> receptors respectively). Brain penetrant.
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| BCC7522 | PAF (C16) |
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Endogenous platelet-activating factor (PAF) and ligand for PAF receptors. Produced by inflammatory cells and a potent chemoattractant for polymorphonuclear neutrophils. Induces increased vascular permeability.
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| BCC7523 | CI 1020 |
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Highly selective, orally active, non-peptide endothelin-A receptor (ETA) antagonist (IC50 values are 0.3 and 480 nM for ETA and ETB receptors respectively). Antihypertensive; blocks ET-1-induced pressor responses following oral administration.
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| BCC7524 | Methimepip dihydrobromide |
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Extremely selective histamine H3 receptor agonist (pKi values are 9.0, 5.7, < 5.0 and < 5.0 for hH3, hH4, hH1 and hH2 receptors respectively). Potently inhibits EFS-evoked contractions of guinea pig ileum (pD2 = 8.26).
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| BCC7525 | (R)-(+)-m-Nitrobiphenyline oxalate |
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α2C-adrenoceptor agonist that potently inhibits cAMP accumulation in CHO cells (EC50 = 38 nM). Behaves as an antagonist at α2A and α2B adrenoceptors (pKb values are 7.11 and 6.07 respectively).
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| BCC7526 | CyPPA |
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Activator of small conductance Ca<sup>2+</sup>-activated K<sup>+</sup> channels that displays selectivity for K<sub>Ca</sub>2.2 (SK2) and K<sub>Ca</sub>2.3 (SK3) channels (EC<sub>50</sub> values are 5.6 and 14 <span class='symbol'>μ</span>M for K<sub>Ca</sub>2.3 and K<sub>Ca</sub>2.2 respectively). Displays no activity at K<sub>Ca</sub>2.1 (SK1) and K<sub>Ca</sub>3.1 (IK) channels.
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