Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN4425 | 6-Hydroxyrubiadin |
| 6-Hydroxyrubiadin has antioxidant activity, EC(50) is 14.7ug/ml. | |
| BCN4427 | Alismol |
| 1. Alismol acts primarily on nerve terminals and inhibits their responses to electrical stimulation by interfering with NAd release. 2. Alismol inhibits mainly Ca2+ influx through a voltage-dependent Ca2+ channel. 3. Alismol holds great promise for use in chemopreventive and chemotherapeutic strategies. 4. Alismol has antihypertensive action. 5. Alismol decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for the prevention of anginal attacks. 6. Alismol has inhibitory effect to MMP3 expression and nitric oxide produced in microglial cells. | |
| BCN1318 | 3,5,9-Trihydroxyergosta-7,22-dien-6-one |
| 1. 3β,5α,9α-Trihydroxy-ergosta-7,22-dien-6-one in the presence of NGF (20 ng/mL) exerts a significant increase in neurite-bearing cells. | |
| BCN4430 | Methyl syringate |
| Methyl syringate is a specific and selective activator of hTRPA1, can regulate food intake and gastric emptying through a TRPA1-mediated pathway and, by extension, can contribute to weight suppression. Methyl syringate has a unique inhibitory activity toward aflatoxin production. Methyl syringate could be effective to suppress hypoxia-induced inflammation, it inhibits the hypoxic induction of COX-2 expression and cell invasion through TRPA1 activation. | |
| BCN4431 | Murraxocin |
| 1. Murraxocin is an insecticidal coumarin. | |
| BCN4432 | Kongensin A |
| 1. Kongensin A is an effective heat shock protein 90 (HSP90) inhibitor that has potential anti-necroptosis and anti-inflammation applications. | |
| BCN4433 | Minumicrolin |
| 1. Minumicrolin might be valuable anti-tumor-promoting agents. 2. Minumicrolin shows mild butyrylcholinesterase inhibition activity. 3. Minumicrolin is a plant growth inhibitor against the 2nd leaf sheath elongation of rice seedlings. 4. Murrangatin exhibits cytotoxicity against cholangiocarcinoma cell line, KKU-100. | |
| BCN4435 | Cerebroside B |
| 1.Cerebroside B1b has antiulcerogenic activity. | |
