Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2753 - 2760 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7316 | Prostaglandin E2 |
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Endogenous prostaglandin and primary product of arachidonic acid/cyclooxygenase pathway. Binds with high affinity to EP1, EP2, EP3 and EP4 receptors (Kd values range between ~ 1 - 10 nM). Influences a wide range of processes including inflammation, smooth muscle relaxation, fertility and gastric mucosal integrity. Regulates vertebrate hematopoietic stem cell (HSC) homeostasis.
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| BCC7317 | SCH 39166 hydrobromide |
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High affinity dopamine D<sub>1</sub>/D<sub>5</sub> receptor antagonist; displays K<sub>i</sub> values of 1.2, 2, 980, 5520, 80 and 731 nM for binding to D<sub>1</sub>, D<sub>5</sub>, D<sub>2</sub>, D<sub>4</sub>, 5-HT and <span class='symbol'>α</span><sub>2a</sub> receptors, respectively.
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| BCC7318 | PNU 282987 |
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Highly selective α7 nAChR agonist (Ki = 26 nM) displaying negligible blockade of α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM). Found to be inactive against a panel of 32 receptors at 1 μM, except 5-HT3 receptors (Ki = 930 nM).
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| BCC7319 | Devazepide |
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Potent, orally active CCK1 (CCK-A) receptor antagonist that displays appetite-stimulant effects. Blocks the anorectic response to CCK-8 and increases food intake in rats following systemic and i.c.v administration.
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| BCC7320 | Tautomycetin |
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Selective inhibitor of protein phosphatase (PP)1 (IC<sub>50</sub> values are 1.6 and 62 nM for PP1 and PP2 respectively). Reduces PDGF-induced vascular smooth muscle cell and mesangial cell proliferation without affecting fibronectin secretion and cellular kinase activation <em>in vivo</em>. Immunosuppressive agent; inhibits proliferation and induces apoptosis in activated T cells.
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| BCC7321 | 15-deoxy-Δ-12,14-Prostaglandin J2 |
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Selective PPAR<span class='symbol'>γ</span> agonist that induces adipocyte differentiation in C3H10Y1/2 fibroblasts (EC<sub>50</sub> = 7 <span class='symbol'>μ</span>M).
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| BCC7322 | Leukotriene B4 |
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Potent lipid inflammatory mediator derived from the 5-lipoxygenase pathway of arachidonic acid metabolism. Binds to BLT1 and BLT2 receptors and acts as a potent chemotactic agent and activator of leukocytes. Also displays antiviral activity towards DNA viruses and retroviruses.
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| BCC7323 | SR 142948 |
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Potent non-peptide neurotensin (NT) receptor antagonist that binds with high affinity (IC50 = 0.32 - 3.96 nM; Ki < 10 nM). Attenuates amphetamine-induced hyperactivity and is orally active in vivo.
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