Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN4243 | Isowighteone |
| 1. Isowighteone, a compound that is not naturally produced in this species, accumulated by medicago truncatula hairy roots expressing LaPT1, indicates a strategy for metabolic engineering of novel antimicrobial compounds in legumes; it may have antimicrobial activity against fungal pathogens of plants. | |
| BCN4245 | Echitamine |
| 1. Echitamine chloride possesses anti-tumour activity in-vitro and in-vivo. | |
| BCN4246 | Xanthoplanine |
| 1. Xanthoplanine fully inhibits the EC(50) ACh responses of both alpha7 and alpha4beta2 nACh receptors with estimated IC(50) values of 9+/-3 microM (alpha7) and 5+/-0.8 microM (alpha4beta2). | |
| BCN4248 | 6-Acetyl-2,2-dimethylchroman-4-one |
| 1. 6-Acetyl-2,2-dimethylchroman-4-one and vanillin show anti-platelet aggregation activity induced by arachidonic acid in vitro. | |
| BCN4249 | Sophoridine |
| Sophoridine has anti-inflammatory, anti-cancer and anti-arrhythmia, and affects the immune and central nervous systems. Early and short-time applying sophoridine has neuroprotective effect min permanent middle cerebral artery occlusion (pMCAO) rat brain by down-regulating TRAF6 and up-regulating p-ERK1/2 expression, ameliorating brain infaction and edema. Sophoridine also possesses antiviral activities against Coxsackievirus B3, by regulating cytokine expression, may represent a potential therapeutic agent for viral myocarditis. | |
| BCN4250 | Sempervirine |
| 1. Sempervirine can unwind circular DNA. 2. Sempervirine shows selective inhibition of in vitro synthesis of cancer DNA . | |
| BCN4252 | Eburicol |
| 1. Eburicol inhibit the large accumulation of C-14 methyl sterols and cell lysis when the content of ergosterol becomes too low in the actively growing cells. 2. Mutations in the Eburicol gene impact on the activity of the Eburicol protein. | |
| BCN4254 | Moracin C |
| 1. Moracin C and D, new phytoalexins from diseased mulberry, are antifungal compounds. 2. Moracin C has potent antibacterial activity, it can inhibit FabI and fatty acid synthesis, it inhibit S. aureus FabI with IC(50) of 83.8 uM. 3. Moracin C has anti-inflammatory effect, it can effectively reduce lipopolysaccharide (LPS) stimulated up-regulation of mRNA and protein expression of iNOS, COX-2, and serval pro-inflammatory cytokines (IL-1β, IL-6 and TNF-α. 4. Moracin may be protective influence in tumor promotion, utilization of Moracin may open a new avenue in the treatment of tumerigenesis. | |
