Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2657 - 2664 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7219 | (+)-Anabasine hydrochloride |
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High affinity neuronal nicotinic ACh receptor partial agonist (K<sub>i</sub> values are 0.058, 0.26 and 7.2 <span class='symbol'>μ</span>M for rat <span class='symbol'>α</span>7, rat <span class='symbol'>α</span>4<span class='symbol'>β</span>2 and fish skeletal muscle nAChRs respectively). Also stimulates Ca<sup>2+</sup>-dependent catecholamine release from rat adrenomedullary cells <em>in vitro</em>.
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| BCC7220 | L-803,087 trifluoroacetate |
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Potent and selective somatostatin sst4 receptor agonist. Ki values are 0.7, 199, 4720, 1280 and 3880 nM for cloned human sst4, sst1, sst2, sst3 and sst5 receptors respectively. Facilitates AMPA-mediated hippocampal synaptic responses in vitro and increases kainate-induced seizures in mice in vivo.
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| BCC7221 | L-817,818 |
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Potent and selective somatostatin sst5 receptor agonist. Ki values are 0.4, 3.3, 52, 64 and 82 nM for cloned human sst5, sst1, sst2, sst3 and sst4 receptors respectively. Inhibits growth hormone release from rat pituitary cells (EC50 = 3.1 nM) and insulin release from mouse pancreatic islets (EC50 = 0.3 nM) in vitro.
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| BCC7222 | PNU 142633 |
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Very selective, high affinity 5-HT1D receptor agonist (Ki values are 6 and > 18000 nM at human 5-HT1D and 5-HT1B receptors respectively). Inhibits sympathetically-induced tachycardic responses and blocks neurogenic plasma protein extravasation in vivo.
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| BCC7223 | Leptomycin B |
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Antifungal antibiotic that is an inhibitor of the nuclear export of proteins; acts by binding directly to and inhibiting CRM1/exportin-1. Inhibits the nuclear export of the HIV regulatory protein Rev and stabilizes p53. Antitumor in vitro and in vivo.
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| BCC7224 | (R,R)-THC |
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Non-steroidal, selective estrogen receptor ligand; agonist at ER<span class='symbol'>α</span> receptor (K<sub>i</sub> = 9.0 nM) and antagonist at ER<span class='symbol'>β</span> receptor (K<sub>i</sub> = 3.6 nM).
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| BCC7225 | MPP dihydrochloride |
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Selective, high affinity silent antagonist at ER<span class='symbol'>α</span> receptors. Displays > 200-fold selectivity for ER<span class='symbol'>α</span> over ER<span class='symbol'>β</span>. K<sub>i</sub> values are 2.7 and 1800 nM at ER<span class='symbol'>α</span> and ER<span class='symbol'>β</span> receptors respectively.
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| BCC7226 | Nomifensine |
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Potent inhibitor of noradrenalin and dopamine uptake (Ki values are 4.7, 26 and 4000 nM for inhibition of noradrenalin, dopamine and 5-HT uptake respectively, in rat brain). Increases central dopamine levels in rats following systemic administration. Displays antidepressant activity.
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