Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2617 - 2624 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7176 | NNC 711 |
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Potent and selective inhibitor of GABA uptake by GAT-1 (IC50 values are 0.04, 171, 1700 and 622 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Anticonvulsant following systemic administration in vivo. Also exhibits cognition-enhancing activity.
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| BCC7177 | NNC 63-0532 |
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Potent non-peptide agonist for the NOP receptor (EC50 = 305 nM, Ki = 7.3 nM); ~ 12-fold selective over other receptors. Centrally active following systemic administration in vivo.
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| BCC7178 | Zacopride hydrochloride |
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Highly potent 5-HT3 receptor antagonist (Ki = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). Antiemetic and anxiolytic following systemic administration in vivo.
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| BCC7179 | WAY 161503 hydrochloride |
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Potent and selective 5-HT2C receptor agonist (Ki = 4 nM; EC50 = 12 nM). Antidepressant following systemic administration in vivo.
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| BCC7181 | SR 33805 oxalate |
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Potent Ca2+ channel antagonist; binds allosterically to the a1-subunit of L-type Ca2+ channels (Kd = 20 pM), at a site distinct from other types of blocker. Shows some selectivity for vascular smooth muscle, inducing vasorelaxation without producing inotropic or chronotropic effects. Inhibits PDGF-stimulated smooth muscle cell proliferation.
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| BCC7182 | E-4031 dihydrochloride |
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Selective blocker of KV11.1 (hERG) channels; inhibits the rapid delayed-rectifier K+ current (IKr). Reversibly prolongs action potential duration in guinea pig papillary muscle and isolated ventricular myocytes, without affecting Na+ or Ca2+ inward currents. Class III antiarrhythmic agent.
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| BCC7183 | Altanserin hydrochloride |
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Potent and selective 5-HT<sub>2A</sub> receptor antagonist (K<sub>i</sub> values are 0.13, 4.55, 40, 62 and 1570 nM at 5-HT<sub>2A</sub>, <span class='symbol'>α</span><sub>1</sub>, 5-HT<sub>2C</sub>, D<sub>2</sub> and 5-HT<sub>1A</sub> respectively). Centrally active following systemic administration <em>in vivo</em>.
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| BCC7184 | Raclopride |
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Selective and potent dopamine D2/D3 receptor antagonist (Ki values are 1.8, 3.5, 2400 and 18000 nM for D2, D3, D4 and D1 receptors respectively). Centrally active following systemic administration in vivo.
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