Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN7197 | Cryptofolione |
| 1. Z-Cryptofolione and Cryptomoscatone D2 as highly efficacious inhibitors of the G(2) checkpoint, G(2) checkpoint inhibitors can force cells arrested in G(2) phase by DNA damage to enter mitosis. 2. Cryptofolione shows moderate cytotoxicity in both macrophages and T. cruzi amastigotes, it also displays a mild inhibitory effect on the promastigote form of Leishmania spp. | |
| BCN7198 | 3,5-Dimethoxyphenol |
| 1. 3,5-Dimethoxyphenol, a cyanogenic aglylactone considered as a marker of Taxus poisoning, being present in all species of Taxus. 2. 3,5-Dimethoxyphenol has potent tyrosinase-inhibiting activity. | |
| BCN6398 | Flavoglaucin |
| 1. Flavoglaucin has anti-inflammatory effects, it shows inhibitory effects on inflammatory mediators via the induction of heme oxygenase-1 in lipopolysaccharide-stimulated RAW264.7 macrophages. 2. Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer. 3. Flavoglaucin shows good binding affinity for human opioid or cannabinoid receptors. 4. Flavoglaucin can inhibit mouse skin tumor promotion in a two-stage carcinogenesis test and appear to be an antitumor promoter. 5. Flavoglaucin exhibits a significant radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) with theIC(50) value of 11.3 microM. | |
| BCN7201 | Diarylcomosol III |
| 1, Diarylcomosol III shows inhibitory effects on melanogenesis in B16 melanoma cells, it is a promising therapeutic agent for the treatment of skin disorders. | |
| BCN7203 | Cryptomoscatone D2 |
| 1. Cryptomoscatone D2 is a highly efficacious inhibitor of the G(2) checkpoint, and G(2) checkpoint inhibitors can force cells arrested in G(2) phase by DNA damage to enter mitosis. | |
| BCN7206 | Epiaschantin |
| 1. (+)-Epiaschantin shows marginal cancer cell line inhibitory activities. 2. (+)-Epiaschantin has anti-platelet aggregation activity. | |
| BCN7207 | Bakkenolide B |
| 1. Bakkenolide B has suppressive properties for allergic and inflammatory responses and may be utilized as a potent agent for the treatment of asthma. | |
| BCN7209 | Eicosanyl caffeate |
| 1. Eicosanyl caffeate has anti-ulcer and moderate antioxidant properties, it exhibits potent elastase inhibitory activity, with the IC(50) value of 0.99 microg/mL. | |
