Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2561 - 2568 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7119 | Neurokinin B (human, porcine) |
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Endogenous tachykinin agonist peptide that shows preference for the NK3 receptor (EC50 = 1 nM).
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| BCC7120 | MRS 1706 |
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Potent and selective adenosine A2B receptor inverse agonist (Ki values are 1.39, 157, 112 and 230 nM for human A2B, A1, A2A and A3 receptors respectively).
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| BCC7121 | SKF 83566 hydrobromide |
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Potent and selective D<sub>1</sub>-like dopamine receptor antagonist (K<sub>i</sub>~ 0.56 nM for D<sub>1</sub>; K<sub>B</sub> = 2 <span class='symbol'>μ</span>M for D<sub>2</sub>). Also antagonist at the vascular 5-HT<sub>2</sub> receptor (K<sub>i</sub> = 11 nM). Displays selective inhibition of adenylyl cyclase 2 (AC2); inactive against AC1 or AC5. Centrally active following systemic administration <em>in vivo</em>.
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| BCC7122 | Ro 32-0432 hydrochloride |
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Selective cell-permeable protein kinase C inhibitor. Displays slight selectivity for conventional PKC isoforms over Ca<sup>2+</sup> and atypical PKC isoforms; binding affinities for rat isoforms are 9, 28, 31, 37 and 108 nM for PKC's <span class='symbol'>α</span>, <span class='symbol'>β</span>Ι, <span class='symbol'>β</span>ΙΙ, <span class='symbol'>γ</span> and <span class='symbol'>ε</span> respectively. Orally available and prevents T cell chronic inflammation <em>in vivo</em>.
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| BCC7123 | Indatraline hydrochloride |
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Potent monoamine uptake inhibitor. Inhibits transporters for 5-HT (SERT), dopamine (DAT) and noradrenalin (NET) (Ki values are 0.42, 1.7 and 5.8 nM respectively). Centrally active following systemic administration in vivo.
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| BCC7124 | NBI 27914 hydrochloride |
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Selective, non-peptide corticotropin-releasing factor1 (CRF1) receptor antagonist (Ki = 1.7 nM); has no activity at CRF2 receptors. Blocks behavioral seizures in vivo.
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| BCC7125 | SCH 79797 dihydrochloride |
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Potent, selective non-peptide PAR<sub>1</sub> receptor antagonist (IC<sub>50</sub> = 70 nM). Inhibits haTRAP-induced- but not <span class='symbol'>γ</span>-thrombin-, ADP- or collagen-induced human platelet aggregation. Also selectively blocks PAR<sub>1</sub> agonist- or thrombin-induced increases in cytosolic Ca<sup>2+</sup> in vascular smooth muscle cells.
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| BCC7126 | NKH 477 |
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Water-soluble analog of forskolin that is a potent activator of adenylyl cyclase; shows some selectivity for cardiac (type V) adenylyl cyclase. Stimulates bronchodilation (EC<sub>50</sub> = 32.6 nM) and is an orally active potent positive chronotrope and hypotensive agent <em>in vivo</em>. Also available as part of the PKA.
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