Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2529 - 2536 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7087 | CGP 78608 hydrochloride |
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Potent and selective NMDA antagonist that acts through the glycine site (IC<sub>50</sub> = 5 nM). Displays > 500-fold selectivity over kainate and AMPA receptors (IC<sub>50</sub> values are 2.7 and 3 <span class='symbol'>μ</span>M respectively). Anticonvulsant <em>in vivo</em> following systemic administration. Also available as part of the NMDA Receptor - Glycine Site.
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| BCC7088 | DPN |
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Highly potent estrogen ER<span class='symbol'>β</span> receptor agonist with a 70-fold selectivity over ER<span class='symbol'>α</span> (EC<sub>50</sub> values are 0.85 and 66 nM respectively). Relaxes mesenteric arteries <em>in vitro</em>. Shown to regulate expression of GluR1, GluR2 and GluR3 in rat hippocampus.
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| BCC7089 | Combretastatin A4 |
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Antitumor, antiangiogenic and antimetastatic agent, in vitro and in vivo. Inhibits tubulin polymerization.
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| BCC7090 | Rimcazole dihydrochloride |
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Antagonist at <span class='symbol'>σ</span> receptors (IC<sub>50</sub> values are 1480 and 386 nM at <span class='symbol'>σ</span><sub>1</sub> and <span class='symbol'>σ</span><sub>2</sub> receptors respectively). Also binds to the dopamine transporter (IC<sub>50</sub> = 57.6 nM) and inhibits dopamine uptake. Reduces the stimulatory effects of cocaine <em>in vivo</em>.
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| BCC7091 | CL 316243 disodium salt |
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Potent and highly selective <span class='symbol'>β</span><sub>3</sub>-adrenoceptor agonist (EC<sub>50</sub> = 3 nM); > 10000-fold selective over <span class='symbol'>β</span><sub>1</sub> and <span class='symbol'>β</span><sub>2</sub> receptors. Increases brown adipose tissue thermogenesis and metabolic rate, and decreases blood insulin and glucose levels following oral administration <em>in vivo</em>.
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| BCC7092 | FR 122047 hydrochloride |
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Selective cyclooxygenase-1 (COX-1) inhibitor (IC<sub>50</sub> values are 0.028 and 65 <span class='symbol'>μ</span>M for COX-1 and COX-2 respectively). Antiplatelet, analgesic and anti-inflammatory following oral administration <em>in vivo</em>.
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| BCC7093 | TMS |
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Potent, selective and competitive inhibitor of cytochrome P450 1B1, an enzyme overexpressed in certain tumors (IC50 = 6 nM). 50- and 520-fold selective over P450 1A1 and 1A2 respectively. Inhibits cancer cell growth in vitro.
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| BCC7094 | SR 59230A hydrochloride |
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Potent and selective <span class='symbol'>β</span><sub>3</sub> adrenoceptor antagonist (IC<sub>50</sub> values are 40, 408 and 648 nM for <span class='symbol'>β</span><sub>3</sub>, <span class='symbol'>β</span><sub>1</sub> and <span class='symbol'>β</span><sub>2</sub> receptors respectively). Orally active <em>in vivo</em>. Also available as part of the <span class='symbol'>β</span>-Adrenoceptor Antagonist.
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