Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN7130 | Myrianthic acid |
| 1. Myrianthic acid shows inhibitory activities on foam cell formation in human monocyte-derived macrophages induced by acetylated low-density lipoproteins at a 50 uM concentration. 2. Myrianthic acid shows anticancer activities. 3. Myrianthic acid is equivalently inhibitive as acetylsalicylic acid (IC50: 57.0 microM) on epinephrine induced platelet aggregation. | |
| BCN7134 | Dasycarpol |
| 1. Dasycarpol shows moderate inhibitory activity on lung cancer cell line A549. 2. 9beta-Hydroxyfraxinellone(Dasycarpol) shows significant neuroprotective activity against glutamate-induced neurotoxicity in primary cultures of rat cortical cells at a concentration of 0.1 microM. | |
| BCN7139 | Salaspermic acid |
| 1. Salaspermic acid is an inhibitor of HIV reverse transcriptase and HIV replication in H9 lymphocyte cells. | |
| BCN7140 | Gardenolic acid B |
| 1. Gardenolic acid B shows promising hepatoprotective effects on nitrofurantoin-induced cytotoxicity in human liver-derived Hep G2 cells. 2. Gardenolic acid B shows significant effects on terminating early pregnancy in rats. | |
| BCN7141 | Isolimonexic acid |
| 1. Isolimonexic acid exhibits cytotoxicity on MCF-7 cell lines. 2. Isolimonexic acid inhibits Panc-28 cancer cell growth. | |
| BCN7142 | Lucidadiol |
| 1. Lucidadiol possesses inhibitory activity against acetylcholinesterase (AChE) with the percentage inhibition at 100 uM. 2. Lucidadiol exhibits butyrylcholinesterase-inhibitory activity at concentrations up to 200 uM. 3. Lucidadiol shows antiviral activity against influenza virus type A and HSV type 1. | |
| BCN7144 | Gancaonin I |
| 1. Gancaonin I exhibits anti-BsFtsZ GTPase activities. 2. Gancaonin I shows significant inhibitory activity against B. subtilis, with a MIC value of 5 uM. | |
| BCN7145 | Diammonium glycyrrhizinate |
| 1. Diammonium glycyrrhizinate shows antiviral effect on cell infection by pseudorabies herpesvirus. 2. Diammonium Glycyrrhizinate can reduce inflammatory injury in a rat model of ulcerative colitis, this may occur via suppression of NF-kappaB, TNF-alpha and ICAM-1 in colonic mucosa. 3. Diammonium glycyrrhizinate may possibly protect the liver from injury via two pathways: direct protection of hepatocytes from apoptosis through an IL-6-dependent way and indirect inhibition of T-cell-mediated inflammation through an IL-10-dependent way. 4. Diammonium glycyrrhizinate can attenuate Aβ(1-42)-induced neuronal injury by preventing mitochondrial dysfunction and oxidative stress and improve cognitive impairment in Aβ(1-42)-induced AD mice, indicating that it exerts potential beneficial effects on AD. 5. Diammonium glycyrrhizinate can inhibit airway smooth muscle proliferation possibly through up- regulation of PPARγ in a murine model of chronic asthma. | |
