Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2553 - 2560 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7111 | SC 560 |
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Highly selective cyclooxygenase-1 (COX-1) inhibitor (IC<sub>50</sub> values are 0.009 and 6.3 <span class='symbol'>μ</span>M for COX-1 and COX-2 respectively). Inhibits COX-1-derived platelet thromboxane B<sub>2</sub>, gastric PGE<sub>2</sub> and dermal PDE<sub>2</sub> production. Significantly reduces ovarian surface epithelial tumor growth <em>in vivo</em>. Orally active.
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| BCC7112 | STO-609 acetate |
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Selective, cell-permeable inhibitor of Ca<sup>2+</sup>-calmodulin-dependent protein kinase kinase (K<sub>i</sub> values are 80 and 15 ng/ml for inhibition of CaM-KK<span class='symbol'>α</span> and CaM-KK<span class='symbol'>β</span> respectively); competes for the ATP-binding site. Displays > 80-fold selectivity over CaMK1, CaMK2, CaMK4, MLCK, PKC, PKA and p42 MAPK.
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| BCC7113 | AG 825 |
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Selective ErbB2 inhibitor (IC<sub>50</sub> values are 0.15 and 19 <span class='symbol'>μ</span>M at ErbB2 and ErbB1 respectively). Preferentially triggers p38 MAP kinase-dependent apoptosis in androgen-independent prostate cancer cells.
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| BCC7114 | 6'-Iodoresiniferatoxin |
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High affinity TRPV1 (VR1) vanilloid receptor partial agonist (K<sub>i</sub> = 0.71 nM; EC<sub>50</sub> = 130 nM at human VR1). Displays partial agonism at human VR1 and full agonism at rat VR1.
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| BCC7115 | Tracazolate hydrochloride |
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Subtype-selective GABAA receptor modulator. Can potentiate or inhibit recombinant GABAA function depending on subunit combination. Enhances native GABAA receptor function and is anxiolytic following systemic administration in vivo.
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| BCC7116 | Roxindole hydrochloride |
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Dopamine D2 autoreceptor agonist, with affinity for D3, D4 and 5-HT1 receptors (pKi values are 8.55, 8.93, 8.23, 9.42, 6.00 and 7.05 for human D2, D3, D4, 5-HT1A, 5-HT1B and 5-HT1D receptors). Inhibits 5-HT uptake and is antidepressant in vivo.
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| BCC7117 | (S)-SNAP 5114 |
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GABA transport inhibitor, showing selectivity for GAT-3 and GAT-2 (IC<sub>50</sub> values are 5, 21 and 388 <span class='symbol'>μ</span>M for hGAT-3, rGAT-2 and hGAT-1 respectively). Increases thalamic GABA levels and is an anticonvulsant following systemic administration <em>in vivo</em>.
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| BCC7118 | HEMADO |
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High affinity and selective adenosine A3 receptor agonist (Ki values are 1.1, 327, 1230 and > 30,000 nM for human A3, A1, A2A and A2B receptors respectively).
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