Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2521 - 2528 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7079 | Suramin hexasodium salt |
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Non-selective P2 purinergic antagonist. Also blocks calmodulin binding to recognition sites and G protein coupling to G protein-coupled receptors. Increases open probability of ryanodine receptor (RyR) channels. Also acts as a competitive α1β2γ2 GABAA receptor antagonist. Anticancer and antiviral agent.
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| BCC7080 | (-)-[3R,4S]-Chromanol 293B |
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Enantiomer that selectively inhibits the slow component of delayed rectifier K<sup>+</sup> current (I<sub>Ks</sub>). Block is use-dependent and 7-fold more potent than the (+)-(3S,4R) enantiomer (IC<sub>50</sub> values are 1.36 and 9.6 <span class='symbol'>μ</span>M respectively). Has negligible inhibitory action at K<sub>V</sub>11.1 (hERG) channels (IC<sub>50</sub> > 30 <span class='symbol'>μ</span>M). Racemate Chromanol 293B also available.
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| BCC7081 | GR 127935 hydrochloride |
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Potent and selective 5-HT1B/1D receptor antagonist (pKi values are 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors). Displays > 100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types. Centrally active following oral administration.
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| BCC7082 | FIT |
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Selective and irreversible <span class='symbol'>δ</span>-opioid agonist (EC<sub>50</sub> = 8 nM); acts by alkylating the receptor.
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| BCC7083 | GR 89696 fumarate |
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Highly potent and selective <span class='symbol'>κ</span>-opioid agonist (IC<sub>50</sub> = 0.04 nM) that may be selective for the putative <span class='symbol'>κ</span><sub>2</sub> receptor. Anti-nociceptive and neuroprotective <em>in vivo</em>.
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| BCC7084 | Oleylethanolamide |
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Lipid mediator and analog of anandamide that is involved in peripheral regulation of feeding. Selective GPR55 agonist (EC<sub>50</sub> values are 0.44, >30 and >30 <span class='symbol'>μ</span>M at GPR55, CB<sub>1</sub> and CB<sub>2</sub> respectively) and PPAR<span class='symbol'>α</span> agonist (EC<sub>50</sub> = 120 nM). Induces satiety through activation of PPAR<span class='symbol'>α</span> and is also a ceramidase inhibitor. Also endogenous agonist at the GPR119 receptor.
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| BCC7085 | GR 231118 |
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Potent neuropeptide Y (NPY) Y1 receptor antagonist (pA2 = 10 and 10.5 at rY1 and hY1, receptors respectively). Also a potent and selective NPY Y4 receptor agonist (pEC50 values are 6.0, 8.6 and 6.1 for rY2, hY4 and rY5 receptors respectively). Suppresses food intake in rats in vivo. Also has affinity for neuropeptide FF (NPFF) receptors in vitro (Ki = 43-73 nM).
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| BCC7086 | MNI-caged-L-glutamate |
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MNI-caged glutamate that rapidly and efficiently releases glutamate when photolysed (300 - 380 nm excitation). Water-soluble, highly resistant to hydrolysis, stable at neutral pH, and pharmacologically inactive at neuronal glutamate receptors (up to mM concentrations). 2.5-fold more efficient at releasing L-glutamate than NI-caged L-glutamate.
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