Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2505 - 2512 of 9359 hot products
| Catalog No. | Product Name |
|---|---|
| BCC7063 | Citalopram hydrobromide |
|
Highly selective and potent 5-HT uptake inhibitor with no effect on noradrenalin or dopamine uptake (IC50 values are 1.8, 8800 and 41000 nM respectively). Has negligible activity at a wide range of receptors.
|
|
| BCC7064 | DuP 697 |
|
Potent and selective inhibitor of cyclooxygenase-2 (IC50 values are 10 and 800 nM for COX-2 and COX-1 respectively). Inhibits prostaglandin synthesis and is anti-inflammatory in vivo. Orally active.
|
|
| BCC7065 | SQ 22536 |
|
Inhibitor of adenylyl cyclase (IC<sub>50</sub> = 1.4 <span class='symbol'>μ</span>M). Inhibits PGE<sub>1</sub>-stimulated increases in cAMP levels in intact human platelets.
|
|
| BCC7066 | MDL 12330A hydrochloride |
|
Inhibitor of adenylyl cyclase. Also inhibits cAMP and cGMP phosphodiesterases, and blocks slow extracellular and store-operated Ca2+ entry into cells.
|
|
| BCC7067 | Ruthenium Red |
|
Blocks Ca2+ uptake and release from mitochondria, and Ca2+ release from ryanodine-sensitive intracellular stores. Also blocks cell membrane-located capsaicin-activated cation channels (IC50 = 14 nM) and voltage-sensitive Ca2+ channels to inhibit neurotransmitter release.
|
|
| BCC7068 | BMY 45778 |
|
Non-prostanoid prostacyclin mimetic that acts as a partial agonist at IP1 prostacyclin receptors. Potently inhibits platelet aggregation in vitro (IC50 = 27-35 nM).
|
|
| BCC7069 | N-Arachidonylglycine |
|
Endogenous anandamide-like compound. Lacks affinity for CB<sub>1</sub> receptors (K<sub>i</sub> > 10 <span class='symbol'>μ</span>M), VR1 receptors (EC<sub>50</sub> > 10 <span class='symbol'>μ</span>M) and anandamide transporters (IC<sub>50</sub> > 50 <span class='symbol'>μ</span>M) but causes hot-plate analgesia in mice when given orally, and suppresses tonic inflammatory pain. Also endogenous GlyT2 inhibitor.
|
|
| BCC7070 | O-2093 |
|
Inhibitor of anandamide uptake (IC<sub>50</sub> = 17.3 <span class='symbol'>μ</span>M) with little or no activity at CB<sub>1</sub>, CB<sub>2</sub>, TRPV1 and FAAH. Intravenous administration inhibits limb spasticity in mice with chronic relapsing experimental allergic encephalomyelitis (CREAE).
|
|