Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2489 - 2496 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7047 | Kenpaullone |
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Potent inhibitor of CDK1/cyclin B and GSK-3<span class='symbol'>β</span> (IC<sub>50</sub> values are 0.4 and 0.23 <span class='symbol'>μ</span>M respectively). Also inhibits CDK2/cyclin A, CDK2/cyclin E and CDK5/cyclin/p35 (IC<sub>50</sub> values are 0.68, 7.5 and 0.85 <span class='symbol'>μ</span>M respectively). Selective over c-src (IC<sub>50</sub> = 15 <span class='symbol'>μ</span>M), casein kinase 2 (IC<sub>50</sub> = 20 <span class='symbol'>μ</span>M), ERK1 (IC<sub>50</sub> = 20 <span class='symbol'>μ</span>M), ERK2 (IC<sub>50</sub> = 9 <span class='symbol'>μ</span>M) and a range of other protein kinases (IC<sub>50</sub> values > 35 <span class='symbol'>μ</span>M). Generates induced pluripotent stem cells (iPSCs) from somatic cells when used in combination with reprogramming factors; can replace Klf4.
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| BCC7048 | CP 339818 hydrochloride |
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Potent, non-peptide KV1.3 channel antagonist that preferentially binds to the C-type inactivated state of the channel (IC50 ~ 200 nM). Inhibits KV1.4 with an IC50 of ~ 300 nM. Selective over KV1.1, KV1.2, KV1.5, KV1.6, KV3.1-4, and KV4.2.
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| BCC7049 | SCH 202676 hydrobromide |
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Sulphydryl-reactive compound that inhibits agonist and antagonist binding to G-protein-coupled receptors. Inhibits a variety of GPCRs including adenosine, opioid, muscarinic, adrenergic and dopaminergic receptors (IC<sub>50</sub> values are 0.1-1.8 <span class='symbol'>μ</span>M).
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| BCC7050 | FPL 64176 |
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Potent activator of L-type Ca<sup>2+</sup> channels (EC<sub>50</sub> = 16 nM). 40-fold more potent than Bay K 8644 as a positive inotrope in guinea pig atria.
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| BCC7051 | (-)-Terreic acid |
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Selective inhibitor of Bruton's tyrosine kinase (BTK). Inhibits the interaction between PKCbII and BTK (IC50 ~ 30 mM) and the catalytic activity of BTK but does not affect the activity of PKC. Has little effect on the activities of Lyn, Syk, PKA, casein kinase I, ERK1, ERK2 and p38 kinases.
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| BCC7052 | YM 022 |
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Extremely potent and highly selective non-peptide CCK2 silent antagonist (Ki values are 68 pM and 63 nM at CCK2 and CCK1 receptors respectively). Acts in vivo to potently inhibit gastrin-induced gastric acid secretion and histidine decarboxylase activation with a long duration of action.
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| BCC7053 | CGP 39551 |
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Potent, selective and competitive NMDA antagonist (Ki = 310 nM for inhibition of [3H]-CPP binding in rat brain). Centrally active upon oral administration in vivo.
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| BCC7054 | SDM25N hydrochloride |
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Potent and highly selective non-peptide <span class='symbol'>δ</span> receptor antagonist (K<sub>i</sub> values are 4.7, 3800 and 7900 nM for <span class='symbol'>δ</span>, <span class='symbol'>κ</span> and <span class='symbol'>μ</span> receptors respectively). More selective than naltrindole.
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