Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN7075 | Acetylisoeugenol |
| Acetylisoeugenol is a mild sensitizer in vivo, it shows good antifungal activities against R. solani and F. oxysporum. | |
| BCN7076 | Asimilobine |
| 1. (-)-Asimilobine displays weak inhibition against Streptococcus mutans (ATCC 25175), with a minimum inhibition concentration (MIC) of 0.25 mg/mL. 2. (-)-Asimilobine shows antioxidative activity. 3. Asimilobine shows anti-acetylcholinesterase (AChE), anti-α-glucosidase, anti-leishmanial and anti-fungal activities. | |
| BCN7077 | Norarmepavine |
| 1. N-norarmepavine shows significant cytotoxic activities against HL-60 carcinoma cell line with inhibitory ratios of 51.43% at concentration of 1 x 10(-5) M. 2. D-(+)- N-norarmepavine exhibits significant inhibitory activity towards adenosine 5'-diphosphate (ADP)-, arachidonic acid (AA)-, collagen-, and/or platelet-activating factor (PAF)-induced platelet aggregation. 3. Norarmepavine shows inhibition against Trypanosoma cruzi. | |
| BCN7079 | N-Methylcoclaurine |
| 1. N-Methylcoclaurine shows binding affinities for the ĸ opioid receptor with the equilibrium dissociation constant (Ki) value of 0.9 ± 0.1 uM. 2. N-methylcoclaurine shows promising butyrylcholinesterase inhibition activities, with the IC50 value of 15.0 ± 1.4 uM. | |
| BCN7082 | Nepetoidin B |
| 1. Nepetoidin B has anti-fungal and anti-bacterial effects. 2. Nepetoidin B shows antiinflammatory effect, it can inhibit LPS-stimulated NO production possibly via modulation of iNOS mediated by MKP-5/NF-κB pathways in RAW 264.7 cells. | |
| BCN7083 | Lumichrome |
| 1. Lumichrome is a derivative of Riboflavin, a vitamin with a key role in maintaining cellular function and health in human and animals. 2. Lumichrome shows photosensitizing effects on the generation of volatiles in soy milk. | |
| BCN7084 | Cytochalasin B |
| 1. Cytochalasin B induces membrane vesicles convey angiogenic activity of parental cells. 2. Cytochalasin B can exert its inhibitory effect on DNA synthesis by inhibiting glucose transport. 3. Cytochalasin B triggers a novel pertussis toxin sensitive pathway in TNF-alpha primed neutrophils. 4. Cytochalasin B is a phytotoxin. | |
| BCN7086 | Psiguadial D |
| 1. Psiguadial D shows significant cytotoxicity toward HepG2 and HepG2/ADM cells. | |
