Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC7507 | Fumitremorgin C |
| 1. Fumitremorgin C is a potent and specific chemosensitizing agent in cell lines selected for resistance to mitoxantrone that do not overexpress P-glycoprotein or multidrug resistance protein. 2. Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. 3. Fumitremorgin C shows an antibacterial activity against Staphylococcus aureus, methicillin-resistant S. aureus, and multidrug-resistant S. aureus. 4. Fumitremorgin C shows cytotoxic activity against HCT-116 tumour cell line. | |
| BCN7234 | Eupahualin C |
| 1. Eupahualin C shows significant activities against cell lines of human chronic myelogenous leukemia (K562) and human bone cancer (U2OS). | |
| BCN7235 | Octadecyl p-coumarate |
| 1. A mixture of (E)-octadecyl p-coumarate and (Z)-octadecyl p-coumarate has antifungal activity , it shows the dose dependent inhibition of the spore germination of Alternaria alternata and A. porri. | |
| BCN7237 | GB 1a |
| 1. GB 1a shows potential in vitro antioxidant activities. | |
| BCN7240 | Demethoxyfumitremorgin C |
| 1. Demethoxyfumitremorgin C inhibits the proliferation of PC3 human prostate cancer cells via the intrinsic (mitochondrial) and extrinsic pathway, followed by downstream events leading to apoptotic cell death, it could therefore, serve as a useful agent to treat human advanced prostate cancer. 2. Demethoxyfumitremorgin C and tryprostatin B are fungal inhibitors of mammalian cell cycle progression at the G(2)/M transition. | |
| BCN7243 | 3,4-Secolupa-4(23),20(29)-diene-3,28-dioic acid |
| 1. 3,4-Secolupa-4(23),20(29)-diene-3,28-dioic acid exhibits potent inhibition of superoxide-anion generation with 86.9 ± 2.8% inhibition at 1 uM. | |
| BCN7245 | Bakkenolide III |
| 1. Bakkenolide III may have cytotoxicity. | |
| BCN7246 | Pseurotin A |
| 1. Pseurotin A has immunosuppressive activity, it inhibits immunoglobulin E(IgE) production in vitro. 2. Pseurotin A shows a moderate effect against the phytopathogenic bacteria Erwinia carotovora and Pseudomonas syringae, with IC50 values of 220 and 112 microg ml(-1), respectively. 3. Pseurotin A shows to be active against the proliferation of four different glioma cells with IC50 values of 0.51-29.3 uM, the targeting multiple metabolic enzymes might be one of the antiglioma mechanisms of pseurotin A. | |
