Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN7212 Baccatin VIII
1. Baccatin VIII exhibits inhibitory effects on HL-60 and MCF-7, with IC50 values of 3.44 and 9.67 uM, respectively.
BCN7215 Rhodamine B
1. Rhodamine B is a well known dye extensively used in thermometric studies.
BCN7216 1,3,6-Trihydroxy-2,5-dimethoxyxanthone
1. 1,3,6-Trihydroxy-2,5-dimethoxyxanthone shows antimutagenic potential, in particular preventing mutations caused by aflatoxin B1 (AFB1) and benzo[a]pyrene (B[a]P). 2. 1,3,6-Trihydroxy-2,5-dimethoxyxanthone may have antifungal activity.
BCN7217 Icariside D2
1. Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 uM, it induces apoptosis via alteration of expression of apoptosis-related proteins and decreased phosphorylation of AKT in HL-60 cells.
BCN7221 Eucannabinolide
1. Eucannabinolide exhibits in vivo antileukemic activity.
BCN7229 Baccatin VI
1. Baccatin VI possesses significant antinociceptive activity against p-benzoquinone-induced abdominal contractions.
BCN7232 Asebogenin
1. Asebogenin shows antiplasmodial activities against both a chloroquine-sensitive and a resistant strain of Plasmodium falciparum. 2. Asebogenin can inhibit the proliferation of murine B cells. 3. Asebogenin has anti-bacterial activity, it shows inhibitory activity against S. aureus and methicillin-resistant S. aureus (IC50 of 10 and 4.5 micrograms/ml, respectively) .
BCN7233 Asebotin
1. Asebotin shows anti-influenza A virus activity, it also possesses potent antiviral activity (100% inhibition at the concentration of 1 ug /mL) against highly pathogenic avian influenza strain H5N1. 2. Asebotin can inhibit the proliferation of murine B cells.