Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2585 - 2592 of 9359 hot products
| Catalog No. | Product Name |
|---|---|
| BCC7144 | SKF 77434 hydrobromide |
|
Selective dopamine D1-like receptor partial agonist (IC50 values are 19.7 and 2425 nM for binding to D1-like and D2-like receptors respectively). Centrally active following systemic administration in vivo.
|
|
| BCC7145 | PD 102807 |
|
Selective M4 muscarinic receptor antagonist. IC50 values are 91, 6559, 3441, 950 and 7412 nM for human M4, M1, M2, M3, and M5 receptors respectively.
|
|
| BCC7146 | RU 28318, potassium salt |
|
Potent and selective antagonist for the mineralocorticoid receptor (MR). Inhibits aldosterone production and secretion, and selectively decreases ex-vivo MR binding in the hippocampus of adrenalectomised rats. Also decreases blood pressure in female rats following central administration in vivo.
|
|
| BCC7147 | Cl-HIBO |
|
Subtype-selective and strongly desensitising AMPA receptor agonist; selective for GluR1 and GluR2 subunit-containing receptors (EC<sub>50</sub> values are 4.7, 1.7, 2700 and 1300 <span class='symbol'>μ</span>M for rat recombinant homomeric GluR1, 2, 3 and 4 receptors respectively).
|
|
| BCC7148 | LE 300 |
|
Potent and selective dopamine D1 receptor antagonist (Ki values are 0.08 - 1.9 nM and 6 - 45 nM for D1 and D2 receptors respectively). Also displays moderate affinity for the 5-HT2A receptor (Ki = 20 nM). Active in vivo.
|
|
| BCC7149 | YM 90709 |
|
Novel, selective inhibitor of interleukin-5 (IL-5) (IC50 = 0.45 - 1 mM). Inhibits IL-5-prolonged eosinophil survival and IL-5-induced tyrosine phosphorylation of JAK2 without inhibiting GM-CSF-mediated effects. Inhibits antigen-induced eosinophil and lymphocyte recruitment in rat airways in vivo, without affecting peripheral blood or bone marrow leukocytes.
|
|
| BCC7150 | GW 7647 |
|
Potent and highly selective PPAR<span class='symbol'>α</span> agonist (EC<sub>50</sub> values are 6, 1100 and 6200 nM for human PPAR<span class='symbol'>α</span>, PPAR<span class='symbol'>γ</span> and PPAR<span class='symbol'>δ</span> receptors respectively). Modulates oleate metabolism and mitochondrial enzyme gene expression in mature myotubules <em>in vitro</em>. Has lipid-lowering effects following oral administration <em>in vivo</em>. Reduces NO production in macrophages; exhibits anti-inflammatory properties.
|
|
| BCC7151 | PIT |
|
Purinergic P2Y receptor ligand. Displays irreversible antagonism at P2Y receptors in some smooth muscles but potentiates responses to ATP in other systems (chick brain recombinant P2Y1 receptor and sympathetic/purinergic nerve stimulation).
|
|