Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2409 - 2416 of 9359 hot products
| Catalog No. | Product Name |
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| BCC6966 | MRS 2219 |
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A selective potentiator of ATP-evoked responses at rat P2X<sub>1</sub> receptors (EC<sub>50</sub> = 5.9 <span class='symbol'>μ</span>M).
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| BCC6967 | SR 57227 hydrochloride |
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A high affinity, selective 5-HT3 receptor agonist, active in vivo and CNS penetrant.
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| BCC6968 | SC 19220 |
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Selective EP<sub>1</sub> receptor antagonist (IC<sub>50</sub> = 6.7 <span class='symbol'>μ</span>M for inhibition of [<sup>3</sup>H]-PGE<sub>2</sub> binding to EP<sub>1</sub> transfected COS cells).
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| BCC6969 | (2R,4R)-APDC |
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A highly selective and relatively potent group II metabotropic glutamate receptor agonist. EC<sub>50</sub> values are 0.4, 0.4, > 100, > 100, > 300 and > 300 <span class='symbol'>μ</span>M for human mGlu<sub>2</sub>, mGlu<sub>3</sub>, mGlu<sub>1</sub>, mGlu<sub>5</sub>, mGlu<sub>4</sub> and mGlu<sub>7</sub> receptors respectively. Centrally active following systemic administration <em>in vivo</em>. Also available as part of the Group II mGlu Receptor.
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| BCC6970 | SIB 1893 |
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A highly selective non-competitive antagonist for the metabotropic glutamate mGlu5 receptor subtype; displays an IC50 value of 0.3 μM at hmGlu5, compared with > 100 μM at hmGlu1b, hmGlu2, hmGlu6, hmGlu7 and hmGlu8. Centrally active upon systemic administration in vivo. Positive allosteric modulator at mGlu4 receptors.
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| BCC6971 | SIB 1757 |
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A highly selective antagonist for the mGlu<sub>5</sub> metabotropic glutamate receptor subtype; displays an IC<sub>50</sub> value of 0.4 <span class='symbol'>μ</span>M at hmGlu<sub>5</sub> compared with > 30 <span class='symbol'>μ</span>M at hmGlu<sub>1b</sub>, hmGlu<sub>2</sub>, hmGlu<sub>4</sub>, hmGlu<sub>6</sub>, hmGlu<sub>7</sub> and hmGlu<sub>8</sub>.
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| BCC6972 | MRS 1220 |
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A potent and highly selective antagonist at the human A<sub>3</sub> adenosine receptor (K<sub>i</sub> values are 0.65, 305, and 52 nM at hA<sub>3</sub>, rA<sub>1</sub> and rA<sub>2A</sub> respectively. Displays an IC<sub>50</sub> value > 1 <span class='symbol'>μ</span>M for inhibition of binding to rat A<sub>3</sub> receptors).
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| BCC6973 | DH 97 |
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A relatively potent MT2 melatonin receptor antagonist (pKi value = 8.03), displaying 89- and 229-fold selectivity over MT1 and GPR50 (melatonin-related orphan receptor) respectively.
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