Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN6869 | Ruixianglangdusu B |
| 1. Ruixianglangdusu B exhibits immunomodulatory activity. | |
| BCN6875 | Trigoxyphin A |
| 1. Trigoxyphin A exhibits strong cytotoxic activity against HL60 (IC(50): 0.27 microM) and A549 (IC(50): 7.5 microM) tumor cell lines. | |
| BCN6878 | Dehydrodiconiferyl alcohol |
| 1. Dehydrodiconiferyl alcohol shows anti-adipogenic and anti-lipogenic effects in 3T3-L1 cells and primary mouse embryonic fibroblasts. 2. Dehydrodiconiferyl alcohol can modulate the differentiation of Th17 and Th1 cells and suppress experimental autoimmune encephalomyelitis, it may be a potential candidate as an agent for the control of Th17 and Th1-mediated inflammatory diseases. 3. (+)-(2S,3R)-Dehydrodiconiferyl alcohol is an antioxidant, it has an inhibitory effect on VCAM-1 expression via JNK pathway in endothelial cells and therefore may serve as a novel pharmacological agent to improve endothelial dysfunction. | |
| BCN6883 | Isojacareubin |
| 1. Isojacareubin is a potent inhibitor of protein kinase C (PKC), suppresses hepatocellular carcinoma metastasis and induces apoptosis in vitro and in vivo, thus, it as a promising lead compound for the development of new antihepatoma agents. 2. Isojacareubin displays potent activity against H. pylori HP40 clinical isolate with MIC 23.9 uM, which is approximately two times greater than that of the standard drug amoxicillin. | |
| BCN6885 | Sterigmatocystin |
| 1. Sterigmatocystin , a mycotoxin commonly found in foodstuff and feedstuff, has been shown to be a carcinogenic mycotoxin in animal models. 2. Sterigmatocystin shows different toxicological, mutagenic and carcinogenic effects in animals and has been recognized as a 2B carcinogen (possible human carcinogen) by International Agency for Research on Cancer. 3. Sterigmatocystin has certain inhibiting effects on the secretion of IL-2 of human peripheral blood mononuclear cells (HPBMc) in vitro. | |
| BCN6886 | Swietemahalactone |
| 1. Swietemahalactone exhibits antibacterial activity. | |
| BCN6887 | Isocudraniaxanthone B |
| 1. Isocudraniaxanthone B may have antimalarial activity. | |
| BCN6889 | Aphagranin A |
| 1. Aphagranin A exhibits strong antiproliferative activity against the growth of six lines of human cancer cells (MCF-7, A549, HepG2, Bel-7402, SGC-7901, and BGC-823. | |
