Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN6837 | Gancaonin G |
| 1. Gancaonin G shows more moderate antibacterial activity against Streptococcus mutans. 2. Gancaonin G shows antibacterial effects on the MRSA strains with MIC values of 16 microg/ml. | |
| BCN6838 | Euchrestaflavanone B |
| 1. Euchrestaflavanone B may function by inhibiting oncogenic disease, at least in part, through the inhibition of protein kinase CKII activity. 2. Euchrestaflavanone B shows antibacterial activity against Gram positive bacteria, Staphylococcus aureus, Bacillus subtilis and Bacillus cereus. | |
| BCN6841 | 7,4'-Dihydroxy-8-methylflavan |
| 1. 7,4'-Dihydroxy-8-methylflavan can significantly promote mesenchymal stem cells (MSCs) osteogenic differentiation by increasing the levels of alkaline phosphatase (ALP) activity. 2. 7,4'-Dihydroxy-8-methylflavan has free radical scavenging properties. | |
| BCN6842 | 5-Hydroxysophoranone |
| 1. 5-Hydroxysophoranone exhibits high antiplasmodial activity against Plasmodium falciparum (IC50=2.5 microg/mL). | |
| BCN6848 | 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone |
| 1. 5,7,3′,4′-Tetrahydroxy-3-methoxy-8,5′-diprenylflavone shows potent anti-proliferation effects on ER-positive breast cancer MCF-7 cells in vitro, with the IC50 value of 4.41 uM. 2. 5,7,3′,4′-Tetrahydroxy-3-methoxy-8,5′-diprenylflavone can strongly down-regulate expression concentrations of estrogen receptor-α (ER-α) and is able to inhibit tumor growth in a xenograft model of the human breast cancer line BCAP-37 in vivo. | |
| BCN6853 | Taiwanhomoflavone A |
| 1. Taiwanhomoflavone A is cytotoxic with ED50 values of 3.4, 1.0, 2.0 and 2.5 microg/ml, respectively, against KB epidermoid carcinoma of nasopharynx, COLO-205 colon carcinoma, Hepa-3B hepatoma, and Hela cervix tumor cells. | |
| BCN6855 | Pierreione B |
| 1. Pierreione B is an inhibitor of mTOR signaling with strong anticancer activity. 2. Pierreione A and Pierreione B demonstrate solid tumor selectivity with minimal cytotoxicity. | |
| BCN6861 | Haginin A |
| 1. Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB activation, MITF, and also by the subsequent downregulation of tyrosinase and TRP-1 production. 2. Haginin A has radical scavenging activity and mushroom tyrosinase inhibitory activity. | |
