Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2385 - 2392 of 9359 hot products
| Catalog No. | Product Name |
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| BCC6942 | N-(3-Methoxybenzyl)oleamide |
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Macamides (N-(3-methoxybenzyl)oleamide (MAC 18:1), N-(3-methoxybenzyl)linoleamide (MAC 18:2) and N-(3-methoxybenzyl)linolenamide (MAC 18:3) )achieve their neuroprotective effects by binding to CB1 receptors to protect against Mn-induced toxicity in U-87 MG glioblastoma cells. Additionally these macamides, in a manner similar to the analogous endocannabinoid AEA, interact with other targets such as PPARγ to regulate metabolism and energy homeostasis, cell differentiation and inflammation.
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| BCC6943 | CGP 37157 |
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Selective antagonist of the mitochondrial Na<sup>+</sup>-Ca<sup>2+</sup> exchanger (IC<sub>50</sub> = 0.4 <span class='symbol'>μ</span>M).
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| BCC6944 | AM 281 |
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Potent, selective CB1 cannabinoid receptor antagonist/inverse agonist (Ki values are 12 and 4200 nM for CB1 and CB2 receptors respectively). Increases locomotor activity following systemic administration in vivo. Analog of SR141716A (Ki = 14 nM).
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| BCC6945 | AM 404 |
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Competitive and selective inhibitor of carrier-mediated anandamide transport (IC<sub>50</sub> = 1 <span class='symbol'>μ</span>M). Does not activate CB<sub>1</sub> receptors or inhibit anandamide hydrolysis but has been shown to activate native and cloned vanilloid receptors (pEC<sub>50</sub> = 7.4). Active <em>in vivo</em>. Also available in water soluble emulsion .
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| BCC6946 | Telenzepine dihydrochloride |
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Selective high affinity muscarinic M1 receptor antagonist (Ki = 0.94 nM). Inhibits gastric acid secretion.
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| BCC6947 | (S)-(+)-Niguldipine hydrochloride |
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L-type Ca<sup>2+</sup> channel blocker and <span class='symbol'>α</span><sub>1A</sub>-adrenoceptor antagonist; more active enantiomer. (<em>R</em>)-(-)-Niguldipine hydrochloride also available.
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| BCC6948 | BRL 44408 maleate |
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Selective <span class='symbol'>α</span><sub>2A</sub>-adrenoceptor antagonist (K<sub>i</sub> = 1.7 nM and 144.5 nM at <span class='symbol'>α</span><sub>2A</sub> and <span class='symbol'>α</span><sub>2B</sub>-adrenergic receptors respectively). Increases hippocampal noradrenalin release following systemic administration. Also available as part of the <span class='symbol'>α<sub>2</sub></span>-Adrenoceptor.
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| BCC6949 | CGP 12177 hydrochloride |
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Partial agonist at <span class='symbol'>β</span><sub>3</sub>-adrenoceptors. <span class='symbol'>β</span><sub>1</sub>- and <span class='symbol'>β</span><sub>2</sub>-adrenoceptor antagonist (K<sub>i</sub> values are 0.9, 4 and 88 nM for <span class='symbol'>β</span><sub>1</sub>, <span class='symbol'>β</span><sub>2</sub> and <span class='symbol'>β</span><sub>3</sub> receptors respectively).
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